지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
Evaluation of the incidence and risk factors associated with persistent frequency in interstitial cystitis/bladder pain syndrome and the efficacy of antimuscarinic treatment
Evaluation of the incidence and risk factors associated with persistent frequency in interstitial cystitis/bladder pain syndrome and the efficacy of antimuscarinic treatment
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한비뇨기과학회 Investigative and Clinical Urology Investigative and Clinical Urology Vol.58 No.5 KCI등재
- 발행연도
- 2017.1
- 수록면
- 353 - 358 (6page)
이용수
Evaluation of the incidence and risk factors associated with persistent frequency in interstitial cystitis/bladder pain syndrome and the efficacy of antimuscarinic treatment
초록· 키워드
오류제보하기
Purpose: To investigate the incidence and risk factors associated with persistent urinary frequency, and to evaluate the efficacy of antimuscarinic treatment. Materials and Methods: Interstitial cystitis/bladder pain syndrome (IC/BPS) patients complaining of persistent urinary frequency despite improved pain were evaluated. Before initial conventional treatment, each patient completed a voiding diary and symptom questionnaires. After conventional treatment, patients were divided according to the presence of pain and frequency. Improved pain was defined as lesser than 3 points in visual analogue scale, and persistent urinary frequency as >10 times/d. Risk factors for persistent frequency were identified through multivariate analysis. The efficacy of antimuscarinic treatment was assessed by the mean change of frequency. Results: Of 171 IC/BPS patients treated with conventional therapy, 132 had improved pain after 3 months, but 72 had persistent frequency (72 of 132, 54.5%). Patients with persistent frequency had lower voided volume (p=0.008), lower maximal flow rate (p<0.001), lower maximal bladder capacity (p=0.003), and more frequent micturition (p<0.001) at baseline compared to those with improved frequency. Patients who took antimuscarinic agents showed slightly decreased urinary frequency, from 14.6 times/d to 13.5 times/d (p=0.438) after 3 months of medication. No patients showed more than a 20% decrease in frequency with antimuscarinics. Conclusions: About half of the patients with IC/BPS showed persistent frequency, with poor voiding function identified as a risk factor; antimuscarinic treatment was not effective in these patients.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Hanno PM / 2015 / Diagnosis and treatment of interstitial cystitis/bladder pain syndrome: AUA guideline amendment / J Urol 193:1545~1553
Liu HT / 2015 / Alteration of urothelial inflammation, apoptosis, and junction protein in patients with various bladder conditions and storage bladder symptoms suggest common pathway involved in underlying pathophysiology / Low Urin Tract Symptoms 7:102~107
Elliott CS / 2012 / Interstitial cystitis and the overlap with overactive bladder / Curr Urol Rep 13:319~326
김태헌 / 2016 / Persistence and compliance with medication management in the treatment of overactive bladder / Investigative and Clinical Urology 57(2):84~93
Warren JW / 2006 / Using the International Continence Society's definition of painful bladder syndrome / Urology 67:1138~1142
Liu HT / 2015 / Alteration of urothelial inflammation, apoptosis, and junction protein in patients with various bladder conditions and storage bladder symptoms suggest common pathway involved in underlying pathophysiology / Low Urin Tract Symptoms 7:102~107
Elliott CS / 2012 / Interstitial cystitis and the overlap with overactive bladder / Curr Urol Rep 13:319~326
김태헌 / 2016 / Persistence and compliance with medication management in the treatment of overactive bladder / Investigative and Clinical Urology 57(2):84~93
Warren JW / 2006 / Using the International Continence Society's definition of painful bladder syndrome / Urology 67:1138~1142
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