지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 85 - 89 (5page)
이용수
초록· 키워드
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Purpose: This study aimed to verify the efficacy and safety of intravesical treatment with sodium chondroitin sulfate (CS) in patients with overactive bladder (OAB) who are refractory to previous antimuscarinic treatment.
Methods: This study was performed between June 2012 and January 2015 and included 31 consecutive women (mean age, 42.10±7.34 years) with OAB who had been previously treated with two types of antimuscarinic drugs. The results of gynecologic and cystoscopic examinations were normal, and OAB comorbidity was absent. Treatment with intravesical instillations containing 40 mL CS (0.2%; 2 mg/mL) was administered for 6 weeks; after weekly treatments, monthly treatments were administered.
The OAB-validated 8 (OAB-V8) symptom scores, nocturia, frequency, urgency, urge incontinence, and urinary volumes measured by uroflowmetry were evaluated for all the patients. The values obtained before the treatment were statistically compared with those obtained six months after the treatment.
Results: The duration of the symptoms was 18.36±6.19 months. A statistically significant improvement of the patients’ conditions was observed in terms of the OAB-V8 symptom scores, nocturia, frequency, urgency, urge incontinence, and urinary volumes measured by uroflowmetry after the treatment.
Conclusions: Despite the limitations of this study, the outcomes confirmed that CS therapy is safe and effective for the treatment of OAB.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Abrams P / 2002 / The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society /
Acquadro C / 2006 / Translating overactive bladder questionnaires in 14 languages / Urology 67 : 536 ~ 540
Baeurle SA / 2009 / Effect of the counterion behavior on the frictional-compressive properties of chondroitin sulfate solutions / Polymer 50 : 1805 ~ 1813
Brinkmann OA / 2000 / The pathogenesis of interstitial cystitis- -many hypotheses, but etiology remains uncertain / Urologe A 39 : 520 ~ 526
Chancellor MB / 1999 / Intravesical capsaicin and resiniferatoxin therapy: spicing up the ways to treat the overactive bladder / J Urol 162 : 3 ~ 11
Acquadro C / 2006 / Translating overactive bladder questionnaires in 14 languages / Urology 67 : 536 ~ 540
Baeurle SA / 2009 / Effect of the counterion behavior on the frictional-compressive properties of chondroitin sulfate solutions / Polymer 50 : 1805 ~ 1813
Brinkmann OA / 2000 / The pathogenesis of interstitial cystitis- -many hypotheses, but etiology remains uncertain / Urologe A 39 : 520 ~ 526
Chancellor MB / 1999 / Intravesical capsaicin and resiniferatoxin therapy: spicing up the ways to treat the overactive bladder / J Urol 162 : 3 ~ 11
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