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자료유형
학술저널
저자정보
박종신 (성균관대학교) 이다영 (성균관대학교) 이은서 (성균관대학교) 김지현 (성균관대학교) 박세은 (성균관대학교) 박철영 (성균관대학교) 이원영 (성균관대학교) 오기원 (성균관대학교) 박성우 (성균관대학교) 이은정 (성균관대학교)
저널정보
대한내분비학회 Endocrinology and Metabolism Endocrinology and Metabolism Vol.31 No.4
발행연도
2016.1
수록면
559 - 566 (8page)

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Background: We aimed to assess the risk for coronary artery calcification (CAC) according to groups subdivided by body mass index(BMI) and waist circumference (WC) in apparently healthy Korean adults. Methods: Thirty-three thousand four hundred and thirty-two participants (mean age, 42 years) in a health screening program weredivided into three groups according to BMI: <23 kg/m2 (normal), 23 to 25 kg/m2 (overweight), and >25 kg/m2 (obese). In addition,the participants were divided into two groups according to WC. Coronary artery calcium score (CACS) was measured with multidetectorcomputed tomography in all participants. Presence of CAC was defined as CACS >0. Results: When logistic regression analysis was performed with the presence of CAC as the dependent variable, the risk for CAC increasedas BMI increased after adjusting for confounding variables (1.102 [95% confidence interval (CI), 1.000 to 1.216]; 1.284[95% CI, 1.169 to 1.410]; in the overweight and obese groups vs. the normal weight group). When the participants were divided intosix groups according to BMI and WC, the subjects with BMI and WC in the obese range showed the highest risk for CAC (1.321[95% CI, 1.194 to 1.461]) and those with BMI in the overweight range and WC in the obese range showed the second highest riskfor CAC (1.235 [95% CI, 1.194 to 1.461]). Conclusion: Participants with obesity defined by both BMI and WC showed the highest risk for CAC. Those with BMIs in the overweightrange but with WC in the obese range showed the second highest risk for CAC, suggesting that WC as a marker of obesity ismore predictive of CAC than BMI.

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