지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 537 - 546 (10page)
이용수
초록· 키워드
오류제보하기
Background: The objective of the current study was to determine whether there was an association between urinary albumin excretionand cardiovascular disease (CVD) risk by estimating the Framingham Risk Score (FRS) in postmenopausal women without diabetes. Methods: This study was based on data from the Korea National Health and Nutrition Examination Survey, which was conductedby the Korean Ministry of Health and Welfare in 2011 to 2013. Data on 2,316 postmenopausal women from a total of 24,594 participantswas included in the analysis. Results: The mean FRS was significantly different in each of the urinary albumin to creatinine ratio (UACR) subgroups, and it increasedwith UACR. The FRS was 12.69±0.12 in the optimal group, 14.30±0.19 in the intermediate normal group, 14.62±0.26 inthe high normal group, and 15.86±0.36 in the microalbuminuria group. After fully adjusting for potential confounding factors, highnormal levels and microalbuminuria were significantly associated with the highest tertile of FRS ([odds ratio (OR), 1.642; 95% confidenceinterval (CI), 1.124 to 2.400] and [OR, 3.385; 95% CI, 2.088 to 5.488], respectively) compared with the optimal subgroup. High normal levels and microalbuminuria were also significantly associated with a ≥10% 10-year risk of CVD ([OR, 1.853; 95%CI, 1.122 to 3.060] and [OR, 2.831; 95% CI, 1.327 to 6.037], respectively) after adjusting for potential confounding covariates. Conclusion: Urinary albumin excretion reflects CVD risk in postmenopausal women without diabetes, and high normal levels andmicroalbuminuria were independently associated with a higher risk of CVD.
목차
등록된 정보가 없습니다.
참고문헌 (32)
참고문헌 신청
Basi S / 2008 / Microalbuminuria in type 2 diabetes and hypertension: a marker, treatment target, or innocent bystander? / Diabetes Care 31(Suppl 2):S194~S201
Rachmani R / 2000 / Considerations about the threshold value of microalbuminuria in patients with diabetes mellitus: lessons from an 8-year follow-up study of 599 patients / Diabetes Res Clin Pract 49:187~194
de Zeeuw D / 2006 / Microalbuminuria as an early marker for cardiovascular disease / J Am Soc Nephrol 17:2100~2105
Hillege HL / 2001 / Microalbuminuria is common, also in a nondiabetic, nonhypertensive population, and an independent indicator of cardiovascular risk factors and cardiovascular morbidity / J Intern Med 249:519~526
Kweon SS / 2012 / Prevalence of albuminuria and associated cardiovascular risk factors: a community cohort in Namwon City, Korea / Diabetes Res Clin Pract 97:492~498
Rachmani R / 2000 / Considerations about the threshold value of microalbuminuria in patients with diabetes mellitus: lessons from an 8-year follow-up study of 599 patients / Diabetes Res Clin Pract 49:187~194
de Zeeuw D / 2006 / Microalbuminuria as an early marker for cardiovascular disease / J Am Soc Nephrol 17:2100~2105
Hillege HL / 2001 / Microalbuminuria is common, also in a nondiabetic, nonhypertensive population, and an independent indicator of cardiovascular risk factors and cardiovascular morbidity / J Intern Med 249:519~526
Kweon SS / 2012 / Prevalence of albuminuria and associated cardiovascular risk factors: a community cohort in Namwon City, Korea / Diabetes Res Clin Pract 97:492~498
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