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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Menopause contributes to an increase in visceral fat mass and a decrease in muscle protein synthesis. Therefore, we performed this study to examine their relationship how effect the changes of body composition as obesity and sarcopenia on metabolic syndrome (MS) as a predictor of cardiovascular disease in postmenopausal women.
Methods: Using data from the Korean National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011, we estimated that 4,183 postmenopausal women underwent dual energy X-ray absorptiometry scans. Sarcopenia was defined as an appendicular skeletal muscle mass divided by body weight that was less than 1 standard deviation below the sex specific mean for the young reference group. After classification into four groups, the results were adjusted with menopausal age and hormonal treatment. The relationship between sarcopenic obesity (SO) and MS in postmenopausal women was analyzed by logistic regression analysis in a complex sampling. Results: In an unadjusted model, the odds ratio (OR) of MS for sarcopenia was 1.94 (95% confidence interval [CI], 1.52-2.49); the obesity group had an OR of 4.55 (95% CI, 3.63-5.71); and distinctly, the SO group had an OR of 6.26 (95% CI, 5.10-7.70). Even though there was controlling for variable adjustment, no definite difference was seen in the results. Conclusions: Sarcopenia and obesity were associated with MS independent of other metabolic impairment risk factors in both early menopausal and postmenopausal women. The results showed that, in particular, the prevalence of MS has increased more in postmenopausal women compared with previous research.
목차
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참고문헌 (23)
참고문헌 신청
Alberti KG / 2006 / Metabolic syndrome-a new world-wide definition. A Consensus Statement from the International Diabetes Federation / Diabet Med 23 : 469 ~ 480
Baumgartner RN / 1998 / Epidemiology of sarcopenia among the elderly in New Mexico / Am J Epidemiol 147 : 755 ~ 763
Chung JY / 2013 / Body composition and its association with cardiometabolic risk factors in the elderly: a focus on sarcopenic obesity / Arch Gerontol Geriatr 56 : 270 ~ 278
Crawford SL / 2000 / A longitudinal study of weight and the menopause transition: results from the Massachusetts Women’s Health Study / Menopause 7 : 96 ~ 104
Goodpaster BH / 2006 / The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study / J Gerontol A Biol Sci Med Sci
Baumgartner RN / 1998 / Epidemiology of sarcopenia among the elderly in New Mexico / Am J Epidemiol 147 : 755 ~ 763
Chung JY / 2013 / Body composition and its association with cardiometabolic risk factors in the elderly: a focus on sarcopenic obesity / Arch Gerontol Geriatr 56 : 270 ~ 278
Crawford SL / 2000 / A longitudinal study of weight and the menopause transition: results from the Massachusetts Women’s Health Study / Menopause 7 : 96 ~ 104
Goodpaster BH / 2006 / The loss of skeletal muscle strength, mass, and quality in older adults: the health, aging and body composition study / J Gerontol A Biol Sci Med Sci
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