지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 476 - 479 (4page)
이용수
초록· 키워드
오류제보하기
Cholestyramine (CS) is an ion exchange resin, which binds to iodothyronines and would lower serum thyroid hormone level. Theuse of CS added to conventional antithyroid drugs to control thyrotoxicosis has been applied since 1980’s, and several studies indicatethat using CS in combination with methimazole (MZ) produces a more rapid decline in serum thyroid hormones than withonly MZ treatment. Our recent retrospective review of five patients taking high dose MZ and CS, compared to age-, gender-, initialfree thyroxine (T4) level-, and MZ dose-matched 12 patients with MZ use only, showed more rapid decline of both free T4and triiodothyronine levels without more adverse events. CS could be safely applicable short-term adjunctive therapy when firstlineantithyroid medications are not enough to adequately control severe thyrotoxicosis or side effects of antithyroid drug wouldbe of great concern.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Cooper DS / 2005 / Antithyroid drugs / N Engl J Med 352:905~917
Sebastian-Ochoa A / 2008 / Dramatic response to cholestyramine in a patient with Graves’ disease resistant to conventional therapy / Thyroid 18:1115~1117
Li H / 1995 / A hyperthyroid patient with Graves’ disease who was strongly resistant to methimazole : investigation on possible mechanisms of the resistance / Endocr J 42:697~704
Mercado M / 1996 / Treatment of hyperthyroidism with a combination of methimazole and cholestyramine / J Clin Endocrinol Metab 81:3191~3193
Solomon BL / 1993 / Adjunctive cholestyramine therapy for thyrotoxicosis / Clin Endocrinol (Oxf) 38:39~43
Sebastian-Ochoa A / 2008 / Dramatic response to cholestyramine in a patient with Graves’ disease resistant to conventional therapy / Thyroid 18:1115~1117
Li H / 1995 / A hyperthyroid patient with Graves’ disease who was strongly resistant to methimazole : investigation on possible mechanisms of the resistance / Endocr J 42:697~704
Mercado M / 1996 / Treatment of hyperthyroidism with a combination of methimazole and cholestyramine / J Clin Endocrinol Metab 81:3191~3193
Solomon BL / 1993 / Adjunctive cholestyramine therapy for thyrotoxicosis / Clin Endocrinol (Oxf) 38:39~43
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