지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 410 - 415 (6page)
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초록· 키워드
오류제보하기
Background: Hyponatremia developing in hypothyroid patients has been encountered in clinical practice; however, its prevalencehas not been well established. Methods: Thirty patients diagnosed with differentiated thyroid cancer, rendered hypothyroid after surgery and levothyroxinewithdrawal, and who are for radioactive iodine (RAI) ablation were included. Serum sodium concentrations were measuredtwice, at the time of admission for RAI ablation, and before discharge after increased oral fluid intake. The outcome measureswere to determine the prevalence of hyponatremia among hypothyroid patients prior to RAI ablation and after oral hydrationpost-RAI, and to correlate the serum sodium levels pre-RAI and post-RAI with thyroid-stimulating hormone (TSH) concentrationand age. Results: Thirty patients were included, with ages from 23 to 65 years old (median, 40). Two patients (6.7%) were hyponatremicprior to RAI ablation, and eight patients (26.7%) had mild hyponatremia (130 to 134 mEq/L) after RAI and hydration. There wasno significant correlation between TSH levels and serum sodium levels prior to or after RAI. There was also no significant correlationbetween pre- and post-RAI sodium concentration and age. Conclusion: The prevalence of hyponatremia pre-RAI was 6.7%, and 26.7% post-RAI. No significant correlation was noted betweenTSH concentration and age on pre- or post-RAI sodium concentrations. Routine measurement of serum sodium post-RAI/isolation is still not advised. Measurement of sodium post-RAI may be considered in patients who are elderly, with comorbidconditions or on medications.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Baajafer FS / 1999 / Prevalence and severity of hyponatremia and hypercreatininemia in short-term uncomplicated hypothyroidism / J Endocrinol Invest 22:35~39
Hammami MM / 2013 / Acute severe hypothyroidism is not associated with hyponatremia even with increased water intake : a prospective study in thyroid cancer patients / BMC Endocr Disord 13:27
Nozu T / 2011 / Severe hyponatremia in association with I(131)therapy in a patient with metastatic thyroid cancer / Intern Med 50:2169~2174
Lee JE / 2014 / Risk factors for developing hyponatremia in thyroid cancer patients undergoing radioactive iodine therapy / PLoS One 9:e106840
Werner S / 2005 / The thyroid:a fundamental and clinical text / Lippincott Williams & Wilkins :791
Hammami MM / 2013 / Acute severe hypothyroidism is not associated with hyponatremia even with increased water intake : a prospective study in thyroid cancer patients / BMC Endocr Disord 13:27
Nozu T / 2011 / Severe hyponatremia in association with I(131)therapy in a patient with metastatic thyroid cancer / Intern Med 50:2169~2174
Lee JE / 2014 / Risk factors for developing hyponatremia in thyroid cancer patients undergoing radioactive iodine therapy / PLoS One 9:e106840
Werner S / 2005 / The thyroid:a fundamental and clinical text / Lippincott Williams & Wilkins :791
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