지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 502 - 509 (8page)
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초록· 키워드
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We aimed to investigate the value of bone scintigraphy with additional blood pool phase (BSBP), compared with conventional bone scintigraphy (CBS), in the assessment of rheumatoid arthritis (RA). A total of 242 patients (43 males, 199 females; 14-78 years) with arthralgia, and underwent BSBP were retrospectively analyzed. On the first physical examination, active arthritis was found in 128 of the 242 patients. Clinical diagnosis was made by a rheumatologist on the basis of the 1987 American College of Rheumatology (ACR) criteria, which are considered to be the gold standard. The diagnostic performances and prognostic value of BSBP and CBS were analyzed in the total patients with arthralgia and in the patients with arthritis. The sensitivity of BSBP (84.2%, 80/95) were significantly higher than that of CBS (74.8%, 72/95) in the patients with arthralgia (P = 0.039). When BSBP was interpreted with the results of elevated/positive anti-CCP antibody, its accuracy over CBS also became significantly higher (86.0%, 208/242 vs. 83.1%, 201/242 respectively, P = 0.021). The diagnostic odds ratio of BSBP positivity was higher than CBS positivity in the patients with arthralgia (26.0, 12.9-52.4 vs. 21.1, 10.8-41.3) and with arthritis (12.0, 4.9-29.4 vs. 10.0, 4.2-23.4). Both BSBP and CBS appear to provide acceptable accuracy and comparable diagnostic performance for diagnosis of RA. However, in the patients with arthralgia, BSBP was found to be more sensitive than CBS and more accurate when interpreted with the result of anti-CCP antibody. This could help physicians diagnose RA in daily clinical practice.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Grassi W / 1998 / The clinical features of rheumatoid arthritis / Eur J Radiol 27(Suppl 1):S18~S24
Ziff M / 1979 / General mechanisms of inflammation in rheumatoid arthritis / Bull Schweiz Akad Med Wiss 35:275~281
김지영 / 2014 / The Role of Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria / Journal of Korean Medical Science 29(2):204~209
Papathanassiou D / 2009 / Single-photon emission computed tomography combined with computed tomography(SPECT/CT)in bone diseases / Joint Bone Spine 76:474~480
Berná L / 1992 / Technetium-99m human polyclonal immunoglobulin G studies and conventional bone scans to detect active joint inflammation in chronic rheumatoid arthritis / Eur J Nucl Med 19:173~176
Ziff M / 1979 / General mechanisms of inflammation in rheumatoid arthritis / Bull Schweiz Akad Med Wiss 35:275~281
김지영 / 2014 / The Role of Bone Scintigraphy in the Diagnosis of Rheumatoid Arthritis According to the 2010 ACR/EULAR Classification Criteria / Journal of Korean Medical Science 29(2):204~209
Papathanassiou D / 2009 / Single-photon emission computed tomography combined with computed tomography(SPECT/CT)in bone diseases / Joint Bone Spine 76:474~480
Berná L / 1992 / Technetium-99m human polyclonal immunoglobulin G studies and conventional bone scans to detect active joint inflammation in chronic rheumatoid arthritis / Eur J Nucl Med 19:173~176
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