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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: Burkholderia cepacia is one of the key pathogens involved in the nosocomial outbreaks via contaminated supplies. We describe here an experience of recurrent B. cepacia pseudo-bacteremia caused by the contaminated commercial product of 0.5% chlorhexidine solution in a hospital.Methods: B. cepacia bacteremias detected from 30 November to 17 December 2014 were defined as cases. Epidemiological data were collected by reviewing the medical records and interviews with the healthcare workers. Suspected antiseptics were cultured using blood culture media.Results: Using regular active surveillance of microbiological results, 15 B. cepacia isolates were found in 13 patients. Pseudo-bacteremia was suspected in all of the cases based on the clinical analysis of individual patients. Misuse of 0.5% chlorhexidine in its solution rather than its tincture form as a skin antiseptic prior to drawing blood for blood culture procedures was the only identifiable risk factor for B. cepacia pseudo-bacteremia. Culture of 0.5% chlorhexidine solution was negative. Suspending the use of 0.5% chlorhexidine solution and educating healthcare workers on the proper use of the antiseptic ended the outbreak. Conclusion: Regular surveillance of unusual pathogens may lead to early detection of nosocomial outbreaks. Epidemiological analysis is a strong indicator for the source of outbreak even when there is no microbiological evidence of contamination source.
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참고문헌 (14)
참고문헌 신청
Mangram A / 1996 / Nosocomial Burkholderia cepacia outbreaks and pseudo-outbreaks / Infect Control Hosp Epidemiol 17:718~720
Romero-Gómez MP / 2008 / Outbreak of Burkholderia cepacia bacteremia caused by contaminated chlorhexidine in a hemodialysis unit / Infect Control Hosp Epidemiol 29:377~378
Lee CS / 2008 / Hospital-acquired Burkholderia cepacia infection related to contaminated benzalkonium chloride / J Hosp Infect 68:280~282
Nasser RM / 2004 / Outbreak of Burkholderia cepacia bacteremia traced to contaminated hospital water used for dilution of an alcohol skin antiseptic / Infect Control Hosp Epidemiol 25:231~239
Panlilio AL / 1992 / Infections and pseudoinfections due to povidone-iodine solution contaminated with Pseudomonas cepacia / Clin Infect Dis 14:1078~1083
Romero-Gómez MP / 2008 / Outbreak of Burkholderia cepacia bacteremia caused by contaminated chlorhexidine in a hemodialysis unit / Infect Control Hosp Epidemiol 29:377~378
Lee CS / 2008 / Hospital-acquired Burkholderia cepacia infection related to contaminated benzalkonium chloride / J Hosp Infect 68:280~282
Nasser RM / 2004 / Outbreak of Burkholderia cepacia bacteremia traced to contaminated hospital water used for dilution of an alcohol skin antiseptic / Infect Control Hosp Epidemiol 25:231~239
Panlilio AL / 1992 / Infections and pseudoinfections due to povidone-iodine solution contaminated with Pseudomonas cepacia / Clin Infect Dis 14:1078~1083
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