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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 65 - 76 (12page)
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The interaction between ephrin ligands (efn) and their receptors (Eph) is capable of inducing forward signaling, from ligand to receptor, as well as reverse signaling, from receptor to ligand. The ephrins are widely expressed in many tissues, where they mediate cell migration and adherence, properties that make the efn-Eph signaling critically important in establishing and maintaining tissue boundaries. The efn-Eph system has also received considerable attention in skeletal tissues, as ligand and receptor combinations are predicted to mediate interactions between the different types of cells that regulate bone development and homeostasis. This review summarizes our current understanding of efn-Eph signaling with a particular focus on the expression and functions of ephrins and their receptors in bone. © 2016 The Korean Society of Osteoporosis. Publishing services by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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참고문헌 (78)
참고문헌 신청
Edwards CM / 2008 / Eph receptors and ephrin signaling pathways:a role in bone homeostasis / Int J Med Sci 5:263~272
Compagni A / 2003 / Control of skeletal patterning by ephrinB1-EphB interactions / Dev Cell 5:217~230
Davy A / 2004 / Ephrin-B1 forward and reverse signaling are required during mouse development / Genes Dev 18:572~583
Stark DA / 2011 / Eph/ephrin interactions modulate muscle satellite cell motility and patterning / Development 138:5279~5289
Zhao C / 2006 / Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis / Cell Metab 4:111~121
Compagni A / 2003 / Control of skeletal patterning by ephrinB1-EphB interactions / Dev Cell 5:217~230
Davy A / 2004 / Ephrin-B1 forward and reverse signaling are required during mouse development / Genes Dev 18:572~583
Stark DA / 2011 / Eph/ephrin interactions modulate muscle satellite cell motility and patterning / Development 138:5279~5289
Zhao C / 2006 / Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis / Cell Metab 4:111~121
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