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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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This study was aimed to determine the effect of vitamin D on bone formation around implant in the maxilla of osteoporotic rats. Fifteen female rats at 8 weeks-old were divided into three groups: 1) control group, sham-operated rats, 2) ovariectomized only group (OVX) and 3) ovariectomized and vitamin D-administered group (VitD). Eight weeks after the ovariectomy or sham operation, upper right molar was extracted, and an implant was placed at 4 weeks post-extraction. The vitamin D-administered experimental groups were given with 0.1 μg/kg/day via gavage while the OVX group and the control group received vehicle only. All rats in each group were sacrificed at 8 weeks and histologic and micro-computed tomographic (CT) evaluation were performed. According to the histologic observation, newly formed bone close to implant threads was mature with considerable quantity of bone marrow in the VitD group than the OVX group. In micro-CT findings, the VitD groups showed greater radiologic density of peri-implant bone close to implant threads than the OVX group. The results proposed that vitamin D could increase bone formation around implant. This might have clinical implications in dental implant treatment for patients with reduced bone formation capacity.
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참고문헌 (30)
참고문헌 신청
Dieter Busenlechner / 2014 / Long-term implant success at the Academy for Oral Implantology: 8-year follow-up and risk factor analysis / Journal of Periodontal & Implant Science 44(3):102~108
Pyo SW / 2014 / Bone formation on biomimetic calcium phosphate-coated and zoledronateimmobilized titanium implants in osteoporotic rat tibiae / Int J Oral Maxillofac Implants 29:478~484
Le Guehennec L / 2007 / Surface treatments of titanium dental implants for rapid osseointegration / Dent Mater 23:844~854
Alsaadi G / 2008 / Impact of local and systemic factors on the incidence of late oral implant loss / Clin Oral Implants Res 19:670~676
Bougas K / 2013 / Bone apposition to laminin-1 coated implants : histologic and 3D evaluation / Int J Oral Maxillofac Surg 42:677~682
Pyo SW / 2014 / Bone formation on biomimetic calcium phosphate-coated and zoledronateimmobilized titanium implants in osteoporotic rat tibiae / Int J Oral Maxillofac Implants 29:478~484
Le Guehennec L / 2007 / Surface treatments of titanium dental implants for rapid osseointegration / Dent Mater 23:844~854
Alsaadi G / 2008 / Impact of local and systemic factors on the incidence of late oral implant loss / Clin Oral Implants Res 19:670~676
Bougas K / 2013 / Bone apposition to laminin-1 coated implants : histologic and 3D evaluation / Int J Oral Maxillofac Surg 42:677~682
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