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Purpose: Rehabilitation of the incomplete dentition by means of osseointegrated dentalimplants represents a highly predictable and widespread therapy; however, little is knownabout potential risk factors that may impair long-term implant success. Methods: From 2004 to 2012, a total of 13,147 implants were placed in 4,316 patients atthe Academy for Oral Implantology in Vienna. The survival rates after 8 years of follow-upwere computed using the Kaplan-Meier method, and the impact of patient- and implantrelatedrisk factors was assessed. Results: Overall implant survival was 97% and was not associated with implant length(P=0.930), implant diameter (P=0.704), jaw location (P=0.545), implant position (P=0.450),local bone quality (P=0.398), previous bone augmentation surgery (P=0.617), or patientrelatedfactors including osteoporosis (P=0.661), age (P=0.575), or diabetes mellitus(P=0.928). However, smoking increased the risk of implant failure by 3 folds (P<0.001) anda positive history of periodontal disease doubled the failure risk (P=0.001). Conclusions: Summing up the long-term results of well over 10,000 implants at the Academyfor Oral Implantology in Vienna it can be concluded that there is only a limited numberof patients that do not qualify for implant therapy and may thus not benefit from improvedquality of life associated with fixed implant-retained prostheses.

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