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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 296 - 306 (11page)
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초록· 키워드
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While evidence exists for an association between the dietary total antioxidant capacity (DTAC), mortality, metabolic syndrome, and cardiovascular diseases, data about DTAC and renal function, and progression of chronic kidney disease (CKD) are scarce. This study aimed to determine the associations between DTAC, renal function, and progression of CKD in older adults. The present cross-sectional study consisted of 226 older adults aged ≥ 60 years old from five districts of Tehran, Iran. DTAC was estimated using the oxygen radical absorbance capacity (ORAC) method. Dietary intake, socio-demographic data, medical history, and anthropometric measurements were collected using a validated questionnaire. The estimated glomerular filtration rate (eGFR) was assessed from serum creatinine. Albumin to creatinine ratio (ACR) was calculated by dividing albumin concentration by creatinine concentration and reported as mg/g. The DTAC ranged from 112.8 to 2,553.9. Analyses indicated that DTAC was not associated with eGFR (p = 0.35) and ACR (p = 0.91) even after controlling for confounding variables. Additionally, in logistic regression, no association between eGFR < 60 mL/min/1.73 m2 (p = 0.32) and ACR ≥ 30 mg/g (p = 0.32) with DTAC was observed, which was independent of confounding variables. We observed that more compliance with DTAC is not associated with renal function and CKD progression. Further studies are needed to confirm the findings of the present study in larger samples on different populations.
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참고문헌 (39)
참고문헌 신청
Levey AS / 2003 / National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification / Ann Intern Med 139:137~147
Khajehdehi P / 2014 / Prevalence of chronic kidney disease and its contributing risk factors in southern Iran: a cross-sectional adult population-based study / Iran J Kidney Dis 8:109~115
National Kidney Foundation / 2002 / K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification / Am J Kidney Dis 39:S1~S266
Glassock RJ / 2009 / Ageing and the glomerular filtration rate: truths and consequences / Trans Am Clin Climatol Assoc 120:419~428
Food and Drug Administration / 1998 / Guidance for industry: pharmacokinetics in patients with impaired renal function—study design, data analysis, and impact on dosing and labeling / US Department of Health and Human Services
Khajehdehi P / 2014 / Prevalence of chronic kidney disease and its contributing risk factors in southern Iran: a cross-sectional adult population-based study / Iran J Kidney Dis 8:109~115
National Kidney Foundation / 2002 / K/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification / Am J Kidney Dis 39:S1~S266
Glassock RJ / 2009 / Ageing and the glomerular filtration rate: truths and consequences / Trans Am Clin Climatol Assoc 120:419~428
Food and Drug Administration / 1998 / Guidance for industry: pharmacokinetics in patients with impaired renal function—study design, data analysis, and impact on dosing and labeling / US Department of Health and Human Services
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