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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 13 - 24 (12page)
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We evaluated the effect of Byeol-Gab Extract (BGE) on testicular injury in the mouse after radiation exposure. BGE (50 mg/kg) was administrated to male C57BL/6 mice by P.O for ten days before radiation exposure, and histological parameters were assessed at 6 h and 35 days post 5 Gy irradiation. The BGE attenuated radiation-induced apoptosis in germ cells after 6 h after irradiation. BGE protected testicular morphological changes, such as changes in seminiferous epithelial height after radiation exposure. BGE treatment significantly increased testis weight compared with irradiation controls at 35 days. The present study suggests that BGE attenuates radiation-induced testicular injury via an anti-apoptotic effect and recovery of spermatogenesis.
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참고문헌 (32)
참고문헌 신청
Chuai Y / 2012 / Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals / Biochem J 442(1):49~56
Howell / 2015 / Shahanshah Khan, Jawahar Singh Adhikari, Moshahid Alam Rizvi, Nabo Kumar Chaudhury. Radioprotective potential of melatonin against 60Co γ-ray-induced testicular injury in male C57BL/6 mice / J Biomed Sci 22(1):61
Otala M / 2004 / Protection from radiation-induced male germ cell loss by sphingosine-1-phosphat e / Biol Reprod 70:759~767
Chuai Y / 2012 / Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals / Biochem J 442:49~56
Priyanka Sharma / 2011 / Radiation-Induce d Testicular Injury and Its Amelioration by Tinospora cordifolia (An Indian Medicinal Plant) Extract / Evid Based Complement Alternat Med. 2011:643847
Howell / 2015 / Shahanshah Khan, Jawahar Singh Adhikari, Moshahid Alam Rizvi, Nabo Kumar Chaudhury. Radioprotective potential of melatonin against 60Co γ-ray-induced testicular injury in male C57BL/6 mice / J Biomed Sci 22(1):61
Otala M / 2004 / Protection from radiation-induced male germ cell loss by sphingosine-1-phosphat e / Biol Reprod 70:759~767
Chuai Y / 2012 / Hydrogen-rich saline attenuates radiation-induced male germ cell loss in mice through reducing hydroxyl radicals / Biochem J 442:49~56
Priyanka Sharma / 2011 / Radiation-Induce d Testicular Injury and Its Amelioration by Tinospora cordifolia (An Indian Medicinal Plant) Extract / Evid Based Complement Alternat Med. 2011:643847
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