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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Recently, melatonergic agents have been gaining much interest in the treatment of mood disorders. The elucidation of the underlying biological mechanisms related to the melatonergic system in mood disorders is warranted to ensure the proper use of melatonergic agents. Changes of the melatonergic system have been investigated in several studies of patients with bipolar disorder (BP) and depression. Accumulating evidence has indicated that patients with BP might exhibit abnormal melatonin secretion patterns, increased light-induced melatonin suppression, altered pineal gland volume, genetically abnormal melatonin synthesis enzyme, and modified melatonin receptors. In this review, the findings of studies performed to explore the association between the melatonergic system and BP are discussed. Moreover, the interpretations and limitations of these findings are described.
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참고문헌 (32)
참고문헌 신청
Claustrat B / 2005 / The basic physiology and pathophysiology of melatonin / Sleep Med Rev 9:11~24
Srinivasan V / 2006 / Melatonin in mood disorders / World J Biol Psychiatry 7:138~151
Srinivasan V / 2012 / Role of melatonin in mood disorders and the antidepressant effects of agomelatine / Expert Opin Investig Drugs 21:1503~1522
Uguz AC / 2016 / The importance of melatonin and mitochondria interaction in mood disorders and schizophrenia: a current assessment / Curr Med Chem 23:2146~2158
Beck-Friis J / 1985 / Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of a low melatonin syndrome / Acta Psychiatr Scand 71:319~330
Srinivasan V / 2006 / Melatonin in mood disorders / World J Biol Psychiatry 7:138~151
Srinivasan V / 2012 / Role of melatonin in mood disorders and the antidepressant effects of agomelatine / Expert Opin Investig Drugs 21:1503~1522
Uguz AC / 2016 / The importance of melatonin and mitochondria interaction in mood disorders and schizophrenia: a current assessment / Curr Med Chem 23:2146~2158
Beck-Friis J / 1985 / Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of a low melatonin syndrome / Acta Psychiatr Scand 71:319~330
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Corrigendum: Changes of the Melatonergic System in Bipolar Disorder: A Literature Review
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