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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 151 - 159 (9page)
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초록· 키워드
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As the world population ages, the number of patients with dementia is expected to increase dramatically in the future. Ginseng (Panax ginseng C.A. Meyer) has many effects such as control of nerve function, control of body fluids and metabolic function, anti-diuretic, sexual enhancement, resistance to stress, improvement of digestion and absorption, and immune boosting effects. Kyung-Ok-Ko is widely used in traditional Korean medicine. The aim of this study is to investigate memory-enhancing properties of 70% ethanolic extracts of ginseng sprouts and modified Kyung-Ok-Ko. Alzheimer’s disease was induced by scopolamine treatment (1 mg/kg, i.p.) in mice. Passive avoidance and Y-maze tasks were performed by the mice to determine the effects of ginseng sprout extract and modified Kyung-Ok-Ko on memory. Ginseng sprout extract and modified Kyung-Ok-Ko significantly enhanced cognitive function and reduced scopolamineinduced cognitive impairment in mice. Compared to Kyung-Ok-Ko, modified Kyung-Ok-Ko had a significant memory-enhancing effect at a lower dose. Our findings suggest that ginseng sprout extract and modified Kyung-Ok-Ko attenuate cognitive impairment in mice.
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등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
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Brookmeyer, R. / 1998 / Projections of Alzheimer’s disease in the united states and the public health impact of delaying disease onset / Am J Public Health 88:1337~1342
Burns, A. / 2009 / Dementia / Brit Med J 338:b75
김영섭 / 2004 / 에탄올 투여로 유도한 생쥐의 인지기능 손상에 대한 길경 추출물의 개선효능 / 생약학회지 35(3):239~243
Crapper, D. R. / 1978 / Brain aging and Alzheimer’s disease / Can Psychiatr Assoc J 23:229~233
Brookmeyer, R. / 1998 / Projections of Alzheimer’s disease in the united states and the public health impact of delaying disease onset / Am J Public Health 88:1337~1342
Burns, A. / 2009 / Dementia / Brit Med J 338:b75
김영섭 / 2004 / 에탄올 투여로 유도한 생쥐의 인지기능 손상에 대한 길경 추출물의 개선효능 / 생약학회지 35(3):239~243
Crapper, D. R. / 1978 / Brain aging and Alzheimer’s disease / Can Psychiatr Assoc J 23:229~233
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