지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 438 - 446 (9page)
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초록· 키워드
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Background/Aims: Chromoendoscopy (CE) has been shown to be superior to white light endoscopy (WLE) for neoplasia detection in inflammatory bowel disease (IBD). We aimed to compare the yield of CE and WLE for the detection of overall neoplasia and advanced neoplasia in IBD. Methods: Patients who underwent surveillance colonoscopy from 1999 to 2017 were identified from our IBD database. CE procedures were compared with their respective WLE controls in a paired comparison, and frequency of all neoplasia, advanced neoplasia, and serrated neoplasia was assessed for both targeted and random biopsies.Results: A total of 290 procedures performed in 98 individuals were identified with a median follow-up 4 years (median 3 colonoscopies/patient). CE and WLE were performed in 159 and 131 episodes, respectively. CE detected neoplasia in 40.9% of colonoscopies versus 23.7% with WLE (<i>P</i>= 0.002). In addition, CE detected more advanced neoplasia (18.2% vs. 6.1%, <i>P</i>= 0.002) and serrated lesions (14.5% vs. 6.1%, <i>P</i>= 0.022). Significantly fewer samples were obtained per procedure with CE (14.9 ± 9.7 vs. 20.9 ± 11.1, <i>P</i>< 0.001). Cancer was diagnosed in 2 cases.Conclusions: CE has a higher detection rate than WLE for advanced neoplasia and serrated lesions in patients with IBD under surveillance. Further prospective studies evaluating the impact of CE on decreasing the risk of interval cancer and colectomy in IBD patients are warranted.
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참고문헌 (39)
참고문헌 신청
김은수 / 2017 / Role of Advanced Endoscopic Imaging Techniques in the Management of Inflammatory Bowel Disease / Clinical Endoscopy 50(5):424~428
Ekbom A / 1990 / Ulcerative colitis and colorectal cancer : a population-based study / N Engl J Med 323:1228~1233
Ekbom A / 1990 / Increased risk of large-bowel cancer in Crohn’s disease with colonic involvement / Lancet 336:357~359
Ruben J. Colman / 2016 / Histological inflammation increases the risk of colorectal neoplasia in ulcerative colitis: a systematic review / Intestinal research 14(3):202~210
Thomas T / 2007 / Meta-analysis : cancer risk of low-grade dysplasia in chronic ulcerative colitis / Aliment Pharmacol Ther 25:657~668
Ekbom A / 1990 / Ulcerative colitis and colorectal cancer : a population-based study / N Engl J Med 323:1228~1233
Ekbom A / 1990 / Increased risk of large-bowel cancer in Crohn’s disease with colonic involvement / Lancet 336:357~359
Ruben J. Colman / 2016 / Histological inflammation increases the risk of colorectal neoplasia in ulcerative colitis: a systematic review / Intestinal research 14(3):202~210
Thomas T / 2007 / Meta-analysis : cancer risk of low-grade dysplasia in chronic ulcerative colitis / Aliment Pharmacol Ther 25:657~668
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