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자료유형
학술저널
저자정보
Takahiro Gonai (Iwate Medical University School of Medicine) Keisuke Kawasaki (Iwate Medical University School of Medicine) Shotaro Nakamura (Iwate Medical University School of Medicine) Shunichi Yanai (Iwate Medical University School of Medicine) Risaburo Akasaka (Iwate Medical University School of Medicine) Kunihiko Sato (Iwate Medical University School of Medicine) Yousuke Toya (Iwate Medical University School of Medicine) Kensuke Asakura (Iwate Medical University School of Medicine) Jun Urushikubo (Iwate Medical University School of Medicine) Yasuko Fujita (Iwate Medical University School of Medicine) Makoto Eizuka (Iwate Medical University School of Medicine) Noriyuki Uesugi (Iwate Medical University School of Medicine) Tamotsu Sugai (Iwate Medical University School of Medicine) Takayuki Matsumoto (Iwate Medical University School of Medicine)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.18 No.1
발행연도
2020.1
수록면
107 - 114 (8page)

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Background/Aims: Magnifying endoscopic classification systems, such as the Japan narrow-band imaging (NBI) Expert Team (JNET) classification, have been widely used for predicting the histologic diagnosis and invasion depth of colorectal epithelial tumors. However, disagreement exists among observers regarding magnifying endoscopic diagnosis, because these classification systems are subjective. We herein investigated the utility of endoscopic microvascular density (eMVD) calculated from magnifying NBI endoscopic images in colorectal tumors. Methods: We reviewed magnifying NBI endoscopic images from 169 colorectal epithelial tumors (97 adenomas, 72 carcinomas/high-grade dysplasias) resected endoscopically or surgically. The eMVD on magnifying NBI endoscopic images was evaluated using image-editing software, and relationships between eMVD and clinical, endoscopic, and pathological findings were retrospectively analyzed. Results: The eMVD in carcinomas (0.152±0.079) was significantly higher than that in adenomas (0.119±0.059, P<0.05). The best cutoff value for distinguishing carcinoma from adenoma was 0.133. Sensitivity, specificity, and accuracy were 56.9%, 67.0%, and 62.7%, respectively. In addition, JNET type 2B tumors showed significantly higher eMVD (0.162±0.079) compared to type 2A tumors (0.111±0.050, P<0.05). Conclusions: The eMVD as determined by magnifying NBI endoscopy is considered to be a possible objective indicator for differentiating colorectal carcinomas from adenomas.

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