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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 570 - 577 (8page)
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Background/Aims: A white substance that is opaque to endoscopic light is sometimes observed in the epithelium during narrowbandimaging with magnifying endoscopy of gastric or colorectal epithelial neoplasms. This prospective observational study aimedto determine whether the morphology of the white opaque substance (WOS) allows differential diagnosis between colorectaladenoma and carcinoma. Methods: A consecutive series of patients with colorectal adenomas or early carcinomas who underwent endoscopic resectionor surgical excision were studied. The morphology of the WOS was determined based on endoscopic images before thehistopathological diagnosis was performed. The primary outcome was the diagnostic performance of an irregular WOS as a markerof colorectal carcinoma. Results: The study analyzed 125 lesions. A total of 33 lesions showed an irregular WOS, and 92 lesions showed a regular WOS. Among the 33 lesions found to show an irregular WOS, 30 were carcinomas. Among the 92 lesions showing a regular WOS, 79 wereadenomas. With irregular WOS as a marker of carcinoma, the diagnostic accuracy was 87%, sensitivity was 91%, and specificity was86%. Conclusions: This study demonstrated the potential usefulness of the morphology of the WOS as a marker for the differentialdiagnosis between adenoma and carcinoma in cases of colorectal epithelial neoplasms.
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