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논문 기본 정보

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학술저널
저자정보
Anthony Horton (Division of Gastroenterology Duke University School of Medicine Durham NC USA) Brian Sullivan (Division of Gastroenterology Duke University School of Medicine Durham NC USA) Katie Charles (Division of Gastroenterology Duke University School of Medicine Durham NC USA) Thasha McIntosh (Durham Veterans Affairs Medical Center Durham NC USA) Andrea Davis (Durham Veterans Affairs Medical Center Durham NC USA) Ziad Gellad (Division of Gastroenterology Duke University School of Medicine Durham NC USA) Rahul Shimpi (Division of Gastroenterology Duke University School of Medicine Durham NC USA) C Prakash Gyawali (Division of Gastroenterology Washington University School of Medicine St Louis MO USA) Amit Patel (Division of Gastroenterology Duke University School of Medicine Durham NC USA)
저널정보
대한소화관운동학회(현 대한소화기능성질환.운동학회) Journal of Neurogastroenterology and Motility (JNM) Journal of Neurogastroenterology and Motility (JNM) Vol.26 No.4
발행연도
2020.1
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455 - 462 (8page)

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Background/AimsEsophageal baseline impedance (BI) can be extracted from pH-impedance tracings as mean nocturnal baseline impedance (MNBI), and from high-resolution impedance manometry (HRIM), but it is unknown if values are similar between acquisition methods across HRIM manufacturers. We aim to assess correlations between MNBI and BI from HRIM (BI-HRIM) from 2 HRIM manufacturers in the setting of physiologic acid exposure time (AET). MethodsHRIM and pH-impedance monitoring demonstrating physiologic AET (< 4%) off proton pump inhibitors were required. BI-HRIM was extracted as the average from 5 cm and 10 cm above the lower esophageal sphincter. Distal BI-HRIM (DBI-HRIM) was also extracted from the most distal channel (Medtronic studies). MNBI was extracted from 6 channels. Concordance between BI-HRIM across manufacturers with MNBI was analyzed. ResultsThirty-six patients met the inclusion criteria (59.6 ± 1.7 years; 22% female; body mass index 30.5 ± 0.7; AET 1.6 ± 0.2%). Although MNBI was similar at all channels (P ≥ 0.18), Diversatek BI-HRIM was lower than Medtronic BI-HRIM (P = 0.003). Overall, BI-HRIM correlated with MNBI at corresponding recording sites, 7 cm and 9 cm (P < 0.05), but not at other sites (P ≥ 0.19). Pearson’s correlations > 0.5 were seen at MNBI at 7 cm for both systems, and at 9 cm for Medtronic. DBI-HRIM correlated with MNBI at 3 cm and 5 cm (P < 0.03), but not at other locations (P > 0.1). ConclusionsWhile numeric differences exist between manufacturers, BI-HRIM correlates with MNBI from corresponding channels in patients with physiologic AET. Comparison with AET elevation is needed to determine correlations between pathologic MNBI with BI-HRIM across manufacturers. The optimal HRIM channels from which BI values should be extracted also warrants further study.
#Electric impedance #Esophageal mucosa #Esophageal pH monitoring #Gastroesophageal reflux

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참고문헌 (36)

참고문헌 신청
Gyawali CP / 2020 / ACG clinical guidelines : clinical use of esophageal physiologic testing / Am J Gastroenterol 115:1412~1428 google schola Patel A / 2018 / Gastroesophageal reflux monitoring / JAMA 319:1271~1272 google schola Roman S / 2017 / Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease : update of the porto consensus and recommendations from an international consensus group / Neurogastroenterol Motil 29:1~15 google schola Patel A / 2015 / Parameters on esophageal pH-impedance monitoring that predict outcomes of patients with gastroesophageal reflux disease / Clin Gastroenterol Hepatol 13:884~891 google schola Patel A / 2016 / GERD phenotypes from pH-impedance monitoring predict symptomatic outcomes on prospective evaluation / Neurogastroenterol Motil 28:513~521 google schola

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