Preintervention risk stratification of renal pelvic cancer and ureteral cancer should differ

Tao Yang; Nan Zhang; Bo Yang; Dalin He; Junjie Fan; Jinhai Fan

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자료유형: 학술저널

저자정보: Tao Yang (the First Affiliated Hospital of Xi'an Jiaotong University) Nan Zhang (the First Affiliated Hospital of Xi'an Jiaotong University) Bo Yang (the First Affiliated Hospital of Xi'an Jiaotong University) Dalin He (the First Affiliated Hospital of Xi'an Jiaotong University) Junjie Fan (the First Affiliated Hospital of Xi'an Jiaotong University) Jinhai Fan (the First Affiliated Hospital of Xi'an Jiaotong University)

저널정보: 대한비뇨기과학회 Investigative and Clinical Urology Investigative and Clinical Urology Vol.61 No.4

발행연도: 2020.1

수록면: 397 - 404 (8page)

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Purpose: To identify different preintervention prognostic factors between renal pelvic cancer (RPc) and ureteral cancer (Uc) and to develop different preintervention risk stratifications for each cancer type. Materials and Methods: A total of 1,768 patients with organ-confined upper urinary tract urothelial carcinoma (1,067 patients with RPc and 701 with Uc) who presented between 2004 and 2015 were selected from the Surveillance, Epidemiology, and End Results database. Clinicopathologic characteristics were compared between RPc and Uc. Univariable and multivariable Cox regression models were used to examine the prognostic ability of the clinicopathologic characteristics with respect to oncology outcomes. Results: Age greater than 75 years was significantly associated with cancer-specific survival (CSS) in RPc patients but not in Uc patients. Tumor size had a significant influence on CSS in Uc patients but not in RPc patients; in contrast, age had an influence in RPc but not in Uc. Unlike CSS, age was significantly associated with overall survival (OS) in both RPc and Uc. Tumor size had an effect on OS in Uc patients but not in RPc patients. Conclusions: The preintervention prognostic factors differed between RPc and Uc. Thus, we should develop separate preintervention risk stratification standards for RPc and Uc. Using these specific preintervention risk stratifications, we may be able to select the most appropriate surgical options for patients in the clinic.

#Prognosis #Risk factors #Ureteral neoplasms

참고문헌 (29)

참고문헌 신청

Rouprêt M / 2018 / European Association of Urology guidelines on upper urinary tract urothelial carcinoma: 2017 update / Eur Urol 73:111~122

Ito K / 2014 / Preoperative risk factors for extraurothelial recurrence in patients with ureteral cancer treated with radical nephroureterectomy / J Urol 191:1685~1692

Cummings KB / 1980 / Nephroureterectomy : rationale in the management of transitional cell carcinoma of the upper urinary tract / Urol Clin North Am 7:569~578

Stewart JH / 1999 / Morphologic evidence that analgesic-induced kidney pathology contributes to the progression of tumors of the renal pelvis / Cancer 86:1576~1582

Ito K / 2016 / Preoperative risk factors for extraurothelial recurrence in N0M0 patients with renal pelvic cancer treated by radical nephroureterectomy / Mol Clin Oncol 4:530~536

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