지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 583 - 597 (15page)
이용수
초록· 키워드
오류제보하기
Background Strongylocentrotus nudus is an important cultured sea urchin species in north China, because its gonad is rich in unsaturated fatty acids, particularly long polyunsaturated fatty acids (LC-PUFAs). These PUFAs play pleiotropic and crucial roles in a wide range of biological process. Objective However, the genes contributing to biosynthesis PUFAs have not been elucidated yet, and the molecular mechanism relative to the difference in PUFA composition between male and female gonad as been revealed but the corresponding has not been understood. Methods In this paper, solexa sequencing based transcriptomic approach was used to identify and characterize the key genes relative to PUFA synthesis and further conducted different expressed genes between male and female gonad. Results A total of 130,124 transcripts and 189330 unigenes were de novo assembled from 64.32 Gb data. Next, these unigenes were subjected to functional annotation by mapping to six public databases, and this process revealed a lot of genes involving in lipid metabolism. In addition, three types of fatty acids front-end desaturase and three species of very long fatty acids elongase were identified and the pathway for PUFA biosynthesis was hypothesized. Last, comparative analysis revealed the higher expression level of Δ5 desaturase, Δ6 desaturase, ELOVL-4, -6 and -7 in male gonad compared with female. Conclusion This results could plausible explain the differ in composition of PUFAs between male and female gonad of sea urchin.
목차
등록된 정보가 없습니다.
참고문헌 (71)
참고문헌 신청
Barnathan G / 2009 / Non-methylene-interrupted fatty acids from marine invertebrates : Occurrence, characterization and biological properties / Biochimie 91(6):671~678
Bazinet RP / 2014 / Polyunsaturated fatty acids and their metabolites in brain function and disease / Nat Rev Neurosci 15:771~785
Beeble A / 2012 / Expression pattern of polyketide synthase-2 during sea urchin development / Gene Expr Patterns 12(1?2):7~10
Bell MV / 2001 / Biosynthesis of eicosapentaenoic acid in the sea urchin Psammechinus miliaris / Lipids 36(1):79~82
Coline Billerey / 2014 / Identification of large intergenic non-coding RNAs in bovine muscle using next-generation transcriptomic sequencing / BMC Genomics 15(1):499
Bazinet RP / 2014 / Polyunsaturated fatty acids and their metabolites in brain function and disease / Nat Rev Neurosci 15:771~785
Beeble A / 2012 / Expression pattern of polyketide synthase-2 during sea urchin development / Gene Expr Patterns 12(1?2):7~10
Bell MV / 2001 / Biosynthesis of eicosapentaenoic acid in the sea urchin Psammechinus miliaris / Lipids 36(1):79~82
Coline Billerey / 2014 / Identification of large intergenic non-coding RNAs in bovine muscle using next-generation transcriptomic sequencing / BMC Genomics 15(1):499
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Endogenously Synthesized n-3 fatty Acids in fat-1 Transgenic Mice Suppresses B Cell Activation
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2022 .12
-
Dietary intake of fat and fatty acids by 1-5-year-old children in Korea : a cross-sectional study based on data from the sixth Korea National Health and Nutrition Examination Survey
Nutrition Research and Practice
2018 .08
-
Dietary intake of fat and fatty acids by 1-5-year-old children in Korea : a cross-sectional study based on data from the sixth Korea National Health and Nutrition Examination Survey
Nutrition Research and Practice
2018 .08
-
Association between serum fatty acid composition and innate immune markers in healthy adults
Nutrition Research and Practice
2016 .04
-
Association between serum fatty acid composition and innate immune markers in healthy adults
Nutrition Research and Practice
2016 .04
-
Dietary intake of fats and fatty acids in the Korean population : Korea National Health and Nutrition Examination Survey, 2013
Nutrition Research and Practice
2015 .12
-
Dietary intake of fats and fatty acids in the Korean population : Korea National Health and Nutrition Examination Survey, 2013
Nutrition Research and Practice
2015 .12
-
Association between fish and shellfish, and omega-3 PUFAs intake and CVD risk factors in middle-aged female patients with type 2 diabetes
Nutrition Research and Practice
2015 .10
-
Association between fish and shellfish, and omega-3 PUFAs intake and CVD risk factors in middle-aged female patients with type 2 diabetes
Nutrition Research and Practice
2015 .10
-
Transcriptome analysis to characterize the genes related to gonad growth and fatty acid metabolism in the sea urchin Strongylocentrotus intermedius
Genes & Genomics
2019 .01
-
Anti-inflammatory effects of Perilla oil consumption in Lipopolysaccharide injected obese male Sprague-Dawley rats
한국지역사회생활과학회 학술대회 자료집
2021 .06
-
Dietary Reference Intake of n-3 polyunsaturated fatty acids for Koreans
Nutrition Research and Practice
2022 .05
-
Dietary Reference Intake of n-3 polyunsaturated fatty acids for Koreans
Nutrition Research and Practice
2022 .05
-
벤토나이트를 산란노계 사료에 첨가시 계란의 지방산조성에 관한 연구
한국환경과학회지
2018 .05
-
Association of dietary intake of total fat and fatty acids with the Omega-3 Index: a cross-sectional analysis of NHANES 2011–2012
Nutrition Research and Practice
2025 .02
-
Association of dietary intake of total fat and fatty acids with the Omega-3 Index: a cross-sectional analysis of NHANES 2011–2012
Nutrition Research and Practice
2025 .02
-
한국 완경 여성의 대사증후군 위험인자와 관련된 식이요인 연구: 2016 ~ 2017 국민건강영양조사 자료 이용
대한지역사회영양학회지
2021 .12
-
Transcriptome sequencing discovers genes related to fatty acid biosynthesis in the seeds of Eucommia ulmoides
Genes & Genomics
2016 .01
-
Immunomodulatory Activities of Body Wall Fatty Acids Extracted from Halocynthia aurantium on RAW264.7 Cells
Journal of Microbiology and Biotechnology
2020 .01
-
Effects of a Δ-9-fatty acid desaturase and a cyclopropane-fatty acid synthase from the novel psychrophile Pseudomonas sp. B14-6 on bacterial membrane properties
극지연구소 초록집
2021 .08
이 논문의 저자 정보
최근 본 자료
댓글(0)
0