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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 201 - 211 (11page)
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초록· 키워드
오류제보하기
Testosterone is a nuclear androgen receptor ligand that controls multiple pathways in brain. In addition to the active biosynthesis of steroids in classic steroidogenic organs such as gonads, adrenals and placenta, testosterone also produced in astrocyte cells of brain. Testosterone and its level must be regulated in brain; because, it directly and indirectly affects memory and several key behavioral characteristics. The significance of sound waves on key enzymes that regulate levels of testosterone in brain has not been investigated. The aim of our study was to examine physical stress of such as sound on induction behavioral changes in animal models. According to the current study, sound waves with 528 Hz frequency in 100 dB intensity induce testosterone production in brain by enhancing StAR and SF-1 and reducing P450 aromatase gene expression. Frequency of 528 Hz also reduces total concentration of reactive oxidative species in brain tissue. Prolonged exposure to this sound wave showed reduction of anxiety related behaviors in rats. The results reveal that reduced anxiety is related to increased concentration of testosterone in brain. This study may lead to ascertain a possible therapy in which sounds may be utilized to reduce anxiety in individual.
목차
등록된 정보가 없습니다.
참고문헌 (40)
참고문헌 신청
Ahlbom E / 2001 / Testosterone protects cerebellar granule cells from oxidative stress-induced cell death through a receptor mediated mechanism / Brain Res 892:255~262
Aikey JL / 2002 / Testosterone rapidly reduces anxiety in male house mice(Mus musculus) / Horm Behav 42:448~460
Alexander LD / 2010 / Exposure to low amounts of ultrasound energy does not improve soft tissue shoulder pathology : a systematic review / Phys Ther 90:14~25
Aloisi AM / 2010 / Aromatase and 5-alpha reductase gene expression : modulation by pain and morphine treatment in male rats / Mol Pain 6:1
Altman FP / 1976 / Tetrazolium salts and formazans / Prog Histochem Cytochem 9:1~56
Aikey JL / 2002 / Testosterone rapidly reduces anxiety in male house mice(Mus musculus) / Horm Behav 42:448~460
Alexander LD / 2010 / Exposure to low amounts of ultrasound energy does not improve soft tissue shoulder pathology : a systematic review / Phys Ther 90:14~25
Aloisi AM / 2010 / Aromatase and 5-alpha reductase gene expression : modulation by pain and morphine treatment in male rats / Mol Pain 6:1
Altman FP / 1976 / Tetrazolium salts and formazans / Prog Histochem Cytochem 9:1~56
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