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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 219 - 226 (8page)
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초록· 키워드
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The features of antibacterial activity of chitosan with different molecular weight and with antibiotics are discussed in this study. Depolymerization of high molecular weight chitosan(HMWC) mediated by enzymatic effects was observed in the concentration of enzyme immobilized onto a matrix and time dependent manner. Antibacterial activity of chitosan hydrolysates CTSN-P8 and CTSN-B3 in the presence or absence of antibiotics was investigated. Synergistic antibacterial activity of CTSN-P8 with Kanamycin against Staphylococcus aureus and E. coli was observed based on the dependence of molecular weight of chitosan. On the other hand, significant antifungal activity of CTSN-B3 was observed in morphological changes of Penicillium italicum. Our data demonstrate the critical importance of microbial species and the size of chitosan that can provide some potent biologically activity without significant depressive activity of antibiotics.
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참고문헌 (32)
참고문헌 신청
Zou, P / 2016 / Advances in characterisation and biological activitiesof chitosan and chitosan oligosaccharides / Food Chem 190:1174~1181
최장용 / 2016 / Application of chitosan and chitosan derivatives as biomaterials / Journal of Industrial and Engineering Chemistry 33:1~10
Aranaz, I / 2018 / On the ability of low molecular weight chitosan enzymatically depolymerized to produce and stabilize silver nanoparticles / Biomim 3:21
Mohamed, F. H / 2018 / The potentiality of using chitosan and its enzymatic depolymerized derivative chito-oligosaccharidesas immunomodulators / JAPS 8(12):132~139
Younes, I / 2014 / Influence of acetylation degree and molecular weight of homogeneous chitosans on antibacterial and antifungal acti-vities / Int. J. Food Microbiol 185:57~63
최장용 / 2016 / Application of chitosan and chitosan derivatives as biomaterials / Journal of Industrial and Engineering Chemistry 33:1~10
Aranaz, I / 2018 / On the ability of low molecular weight chitosan enzymatically depolymerized to produce and stabilize silver nanoparticles / Biomim 3:21
Mohamed, F. H / 2018 / The potentiality of using chitosan and its enzymatic depolymerized derivative chito-oligosaccharidesas immunomodulators / JAPS 8(12):132~139
Younes, I / 2014 / Influence of acetylation degree and molecular weight of homogeneous chitosans on antibacterial and antifungal acti-vities / Int. J. Food Microbiol 185:57~63
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