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논문 기본 정보

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학술저널
저자정보
Chung Sang Wan (Division of Rheumatology Department of Internal Medicine Kyung Hee University Hospital School of Me) 최지영 (경희대학교) 이상훈 (경희대학교) 송란 (경희대학교) 양형인 (경희대학교) 홍승재 (경희대학교) 이연아 (경희대학교)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.35 No.31
발행연도
2020.1
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1 - 9 (9page)

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Background: To elucidate the achievement rates of imaging remission and to examine the characteristics associated with imaging remission status among patients with rheumatoid arthritis (RA) who have attained clinical remission. Methods: Ninety-seven patients with RA patients who had attained clinical remission, defined by DAS28-ESR < 2.6 were enrolled. Power Doppler ultrasonography (PDUS) was performed on 16 joints and 2 tendons, including the first to third metacarpophalangeal, second and third proximal interphalangeal, radiocarpal (RC), second and third metatarsophalangeal joints, and extensor carpi ulnaris tendons. They were graded based on a dichotomous assessment. The clinical and laboratory data of patients who had attained imaging remission were compared to those of patients who had attained only clinical remission. Results: The imaging remission rate was 51.5% in patients who had attained clinical remission. Forty-seven patients (48.5%) were PDUS positive. Power Doppler was detected most frequently in the right RC joint (n = 40). PDUS positive patients had higher evaluator global assessment (EGA) scores (P < 0.001) than PDUS negative patients. PDUS positive patients also had higher clinical disease activity index and simplified clinical disease activity index scores than PDUS negative patients. Patients who had attained imaging remission had lower pain scores and used nonsteroidal anti-inflammatory drugs less frequently. Patients who had attained imaging remission had higher rheumatoid factor (RF) and anti- cyclic citrullinated peptide levels. A low EGA score was found to be a predictor of imaging remission achievement among patients who had attained clinical remission. Conclusion: Only 51.5% of the patients with RA who had attained clinical remission were also in imaging remission. Patients who had attained imaging remission had lower EGA scores and higher RF levels than patients who had attained only clinical remission.
#Rheumatoid Arthritis #Ultrasonography #Inflammation #Synovitis

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참고문헌 (27)

참고문헌 신청
Firestein GS / 2003 / Evolving concepts of rheumatoid arthritis / Nature 423(6937):356~361 google schola Schoels M / 2012 / Treating rheumatoid arthritis to target : evidence-based recommendations for enhanced disease management / Reumatol Clin 8(1):1~2 google schola Singh JA / 2016 / 2015 American College of Rheumatology guideline for the treatment of rheumatoid arthritis / Arthritis Rheumatol 68(1):1~26 google schola Smolen JS / 2020 / EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological diseasemodifying antirheumatic drugs : 2019 update / Ann Rheum Dis 79(6):685~699 google schola Smolen JS / 2016 / Treating rheumatoid arthritis to target : 2014 update of the recommendations of an international task force / Ann Rheum Dis 75(1):3~15 google schola

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