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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 48 - 48 (1page)
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Robust recording of environmental and biological information over time has been a key challenge limiting the development of useful cell-based sentinels that can monitor environments and cellular states in open settings. In this talk, I describe a new framework to store environmental and biological temporal information directly into the genomes of a bacterial population. Using this framework, we recently developed a “biological tape recorder” in which biological signals trigger intracellular DNA production that is then recorded by the CRISPR-Cas adaptation system. This approach ... 전체 초록 보기
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