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논문 기본 정보

자료유형
학술저널
저자정보
Park Jae Woo (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit) Yoo Jeong-Ju (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit) Kim Sang Gyune (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit) Jeong Soung Won (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit) Jang Jae Young (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit) Lee Sae Hwan (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit) Kim Hong Soo (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit) Lee Jae Myung (Department of Radiology Soonchunhyang University Bucheon Hospital Soonchunhyang University College) Shim Jong Joon (Department of Radiology Soonchunhyang University Bucheon Hospital Soonchunhyang University College) Kim Young Don (Department of Internal Medicine Gangneung Asan Hospital University of Ulsan College of Medicine Gan) Cheon Gab Jin (Department of Internal Medicine Gangneung Asan Hospital University of Ulsan College of Medicine Gan) Jun Baek Gyu (Department of Internal Medicine Gangneung Asan Hospital University of Ulsan College of Medicine Gan) Kim Young Seok (Division of Gastroenterology and Hepatology Department of Internal Medicine Soonchunhyang Universit)
저널정보
거트앤리버 발행위원회 Gut and Liver Gut and Liver 제14권 제6호
발행연도
2020.1
수록면
783 - 791 (9page)

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Background/Aims: Plug-assisted retrograde transvenous obliteration (PARTO) is widely used to manage gastric varices with a portosystemic shunt. It is not clear whether portal pressure and the incidence of complications increase after PARTO. The aim of this study was to determine the changes in portal pressure and the associated changes in liver function, ascites, hepatic encephalopathy, and especially esophageal varix (EV) after PARTO. Methods: From March 2012 to February 2018, 54 patients who underwent PARTO were analyzed retrospectively. The parameters collected included liver function and episodes of cirrhotic complications before and at 1 and 6 months after PARTO. Results: The analysis of 54 patients showed improvement in liver function during the 6-month follow-up period (Model for End-Stage Liver Disease score: change from 11.46±4.35 to 10.33±2.96, p=0.021). Among these 54 patients, 25 patients were evaluated for their hepatic venous pressure gradient (HVPG) before and after PARTO (change from 12.52±3.83 to 14.68±5.03 mm Hg; p<0.001). Twenty-five patients with portal pressure measured before and after PARTO were evaluated for risk factors affecting liver function improvement and EV deterioration. No factor associated with portal pressure was affected by liver function improvement. Post-PARTO portal pressure was a risk factor affecting EV deterioration (HVPG-post: odds ratio, 1.341; 95% confidence interval, 1.017 to 1.767; p=0.037). Conclusions: The artificial blockade of the portosystemic shunt evidently leads to an increase in HVPG. Liver function was improved over the 6-month follow-up period. Portal pressure after PARTO was a significant risk factor for EV deterioration. Portal pressure measurement is helpful for predicting the patient’s clinical outcome.
#Therapeutic embolization #Gastric varices #Portal pressure #Liver cirrhosis #Gelatin sponge

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참고문헌 (28)

참고문헌 신청
Al-Osaimi AM / 2011 / Medical and endoscopic management of gastric varices / Semin Intervent Radiol 28:273~282 google schola Sarin SK / 1992 / Prevalence, classification and natural history of gastric varices : a longterm follow-up study in 568 portal hypertension patients / Hepatology 16:1343~1349 google schola Yeon Seok Seo / 2018 / Prevention and management of gastroesophageal varices / Clinical and Molecular Hepatology 24(1):20~42 dbpia Triantafyllou M / 2014 / Update on gastric varices / World J Gastrointest Endosc 6:168~175 google schola Trudeau W / 1986 / Endoscopic injection sclerosis in bleeding gastric varices / Gastrointest Endosc 32:264~268 google schola

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