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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 758 - 766 (9page)
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초록· 키워드
오류제보하기
Purpose: To assess associations between surveillance intervals in a national hepatocellular carcinoma (HCC) surveillance programand receiving curative treatment and mortality using nationwide cohort data for Korea. Materials and Methods: Using the National Health Insurance Service Database of Korea, we retrospectively identified 3201852 patients,the target population of the national HCC surveillance program, between 2008 and 2017. After exclusion, a total of 64674 HCCpatients were divided based on surveillance intervals: never screened, ≤6 months (6M), 7?12 months (1Y), 13?24 months (2Y),and 25?36 months (3Y). Associations for surveillance interval with the chance to receive curative therapy and all-cause mortalitywere analyzed. Results: The 6M group (51.9%) received curative therapy more often than the other groups (1Y, 48.3%; 2Y, 43.8%; 3Y, 41.3%; neverscreened, 34.5%). Odds ratio for receiving curative therapy among the other surveillance interval groups (1Y, 0.87; 2Y, 0.76; 3Y, 0.77;never screened, 0.57; p<0.001) were significantly lower than that of the 6M group. The hazard ratios (HRs) of all-cause mortalitywere 1.07, 1.14, and 1.37 for 2Y, 3Y, and never screened groups. The HR for the 1Y group (0.96; p=0.092) was not significantly different,and it was lower (0.91; p<0.001) than that of the 6M group after adjustment for lead-time bias. Curative therapy was associatedwith survival benefits (HR, 0.26; p<0.001). Conclusion: HCC surveillance, especially at a surveillance interval of 6 months, increases the chance to receive curative therapy.
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참고문헌 (8)
참고문헌 신청
이광식 / 2015 / Economic Burden of Cancer in Korea during 2000-2010 / Cancer Research and Treatment 47(3):387~398
Korean Liver Cancer Association (KLCA) and National Cancer Center (NCC / 2019 / 2018 Korean Liver Cancer Association–National Cancer Center Korea Practice Guidelines for the Management of Hepatocellular Carcinoma / Korean Journal of Radiology 20(7):1042~1113
차지혜 / 2013 / Feasibility of Sorafenib Combined with Local Radiotherapy in Advanced Hepatocellular Carcinoma / Yonsei Medical Journal 54(5):1178~1185
한광협 / 2016 / Living Donor Liver Transplantation for Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis after Concurrent Chemoradiation Therapy / Yonsei Medical Journal 57(5):1276~1281
서민아 / 2016 / Trends in Cancer Screening Rates among Korean Men and Women: Results of the Korean National Cancer Screening Survey, 2004-2013 / Cancer Research and Treatment 48(1):1~10
Korean Liver Cancer Association (KLCA) and National Cancer Center (NCC / 2019 / 2018 Korean Liver Cancer Association–National Cancer Center Korea Practice Guidelines for the Management of Hepatocellular Carcinoma / Korean Journal of Radiology 20(7):1042~1113
차지혜 / 2013 / Feasibility of Sorafenib Combined with Local Radiotherapy in Advanced Hepatocellular Carcinoma / Yonsei Medical Journal 54(5):1178~1185
한광협 / 2016 / Living Donor Liver Transplantation for Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombosis after Concurrent Chemoradiation Therapy / Yonsei Medical Journal 57(5):1276~1281
서민아 / 2016 / Trends in Cancer Screening Rates among Korean Men and Women: Results of the Korean National Cancer Screening Survey, 2004-2013 / Cancer Research and Treatment 48(1):1~10
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