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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 501 - 509 (9page)
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초록· 키워드
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The aim of this was evaluate the efficacy of lysozyme on growth performance, nutrient digestibility, excreta microflora population, and blood profiles of weanling pigs under Escherichia coli (E. coli) challenge. A total of 30 piglets weaned at 25 days, 7.46 kg body weight, were assigned to three dietary treatments, composed of five replications, two piglets per replication, for 7 days. The dietary treatment groups were negative control (NC; without antibiotics and lysozyme), positive control (PC; NC + antibiotics), lysozyme (NC + 0.1% lysozyme). All piglets were challenged orally with 6 ml suspension, containing E. coli K88 (2 × 109 CFU/mL). Dietary supplementation with lysozyme and PC resulted in no significant differences in average daily gain and gain to feed efficiency. Weanling pigs fed with E. coli challenge with lysozyme and PC treatments had significantly enhanced nutrient retentions of dry matter and energy (p < 0.05); however, there was a tendency to increase nitrogen digestibility. Furthermore, dietary inclusion of lysozyme and antibiotics treatment groups had a beneficial effect on excreta, ileal, and cecal of the fecal microbial population as decreased E. coli (p < 0.05) counts, without effects on lactobacillus counts. A significant effect were observed on a white blood cells, epinephrine and cortisol concentrations were reduced in piglets fed diets containing E. coli challenge with lysozyme and antibiotics supplementation comparison with the NC group. Therefore, the present data indicate that lysozyme in diet could ameliorate the experimental stress response induced by E. coli in piglets by decreasing intestinal E. coli, white blood cells and stress hormones and improving nutrient digestibility.
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참고문헌 (32)
참고문헌 신청
John M. Talent / 1996 / Pilot study of oral polymeric N-acetyl-d-glucosamine as a potential treatment for patients with osteoarthritis / Clinical Therapeutics 18(6):1184~1190
Nathan Grossowicz / 1983 / Methods for Determination of Lysozyme Activity / Methods of Biochemical Analysis 29:435~446
W D Biggar / 1977 / Role of lysozyme in the microbicidal activity of rat alveolar macrophages / Infection and Immunity 16(3):974~982
Hisham R. Ibrahim / 1996 / A Structural Phase of Heat-Denatured Lysozyme with Novel Antimicrobial Action / Journal of Agricultural and Food Chemistry 44(6):1416~1423
Osserman EF / 1976 / Postulated relationships between lysozyme and immunoglobulins as mediators of macrophage and plasma cell functions / Adv Pathobiol 4:98~105
Nathan Grossowicz / 1983 / Methods for Determination of Lysozyme Activity / Methods of Biochemical Analysis 29:435~446
W D Biggar / 1977 / Role of lysozyme in the microbicidal activity of rat alveolar macrophages / Infection and Immunity 16(3):974~982
Hisham R. Ibrahim / 1996 / A Structural Phase of Heat-Denatured Lysozyme with Novel Antimicrobial Action / Journal of Agricultural and Food Chemistry 44(6):1416~1423
Osserman EF / 1976 / Postulated relationships between lysozyme and immunoglobulins as mediators of macrophage and plasma cell functions / Adv Pathobiol 4:98~105
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