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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 605 - 613 (9page)
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초록· 키워드
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This study was conducted to evaluate the effects of dietary supplementation of plant flavonoid (quercetin) on immune parameters, growth performance, and nutrient digestibility in growing pigs challenged with Escherichia coli lipopolysaccharide (LPS). A total of 40 crossbred ([Landrace × Yorkshire] × Duroc) growing pigs; initial body weight (BW) of 26.95 ± 1.26 kg were used in a six-week experimental trial. Pigs were randomly allocated into one of four treatment groups in a 2 × 2 factorial arrangement with the following factors; without LPS challenge and with LPS challenge (day 21) supplemented with or without 0.1% flavonoid according to BW (2 replicate pens per treatment with 2 gilts and 3 barrows per pen). The singledose LPS (100 ug / kg BW) injection showed trends tended to be increased in interleukin-6 (IL-6) after 2 h and 6 h of challenge compared with unchallenged pigs. However, other measured immune indices (white blood cell, immunoglobulin G, lymphocyte, and tumor necrosis factor), growth performance, and nutrient digestibility were not significantly different between challenged and non-challenged animals. The supplementation of flavonoid significantly increased (p < 0.05) average daily gain (ADG) during day 0?21, tended to increase dry matter and nitrogen digestibility, significantly reduced IL-6, increased Ig-G and WBC concentrations and increased lymphocytes percentage regardless of LPS challenge.
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참고문헌 (34)
참고문헌 신청
Vidanarachchi JK / 2005 / Phytobiotics : alternatives to antibiotic growth promoters in monogastric animal feeds / Recent Adv Anim Nutr Aust 15:131~144
Petr Hodek / 2002 / Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450 / Chemico-Biological Interactions 139(1):1~21
A D Agrawal / 2011 / Pharmacological Activities of Flavonoids: A Review / International Journal of Pharmaceutical Sciences and Nanotechnology 4(2):1394~1398
김정미 / 2008 / Anti-platelet Effects of Flavonoids and Flavonoid-glycosides from Sophora japonica / Archives of Pharmacal Research 31(7):886~890
Cui Zhu / 2015 / Dietary soy isoflavone attenuated growth performance and intestinal barrier functions in weaned piglets challenged with lipopolysaccharide / International Immunopharmacology 28(1):288~294
Petr Hodek / 2002 / Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450 / Chemico-Biological Interactions 139(1):1~21
A D Agrawal / 2011 / Pharmacological Activities of Flavonoids: A Review / International Journal of Pharmaceutical Sciences and Nanotechnology 4(2):1394~1398
김정미 / 2008 / Anti-platelet Effects of Flavonoids and Flavonoid-glycosides from Sophora japonica / Archives of Pharmacal Research 31(7):886~890
Cui Zhu / 2015 / Dietary soy isoflavone attenuated growth performance and intestinal barrier functions in weaned piglets challenged with lipopolysaccharide / International Immunopharmacology 28(1):288~294
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