지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.1
- 수록면
- 37 - 45 (9page)
이용수
초록· 키워드
오류제보하기
Background: Local hyperthermia is recommended for the treatment of patients with fixed cutaneous sporotrichosis, though the effectiveness and mechanisms of action remain elusive. While neutrophils represent the main inflammatory cells associated with sporotrichosis lesions, the issue of whether hyperthermia is involved with interactions between neutrophils and Sporothrix globosa remains unclear. Objective: To evaluate the effect of local hyperthermia on sporotrichosis and determine whether local hyperthermia involves effects of neutrophils against Sporothrix. Methods: For the in vivo study, mice were infected with yeast cells of S. globosa followed by treatment with local hyperthermia. In vitro, an isolated Sporothrix strain was co-cultured with or without neutrophils and subjected under different temperatures. Immunofluorescence was used to assess the formation of neutrophil extracellular trap (NETs) were formed under these different culture conditions and the number of fungi colony forming units were compared. Results: Hyperthermia was significantly more effective in clearing the lesions in the mouse model, as compared to sham treatment. Neutrophils failed to exert any fungicidal effects against S. globosa in response to hyperthermia. Moreover, NETs were formed after interaction with S. globosa, and the percentage of NETs formed was not significantly different at 41oC or 37oC. Conclusion: While hyperthermia could serve as an effective therapy for fixed cutaneous sporotrichosis, this ability does not involve the formation of NETs.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
A Case of Sporotrichosis Caused by Sporothrix globosa in Japan
Annals of Dermatology
2016 .01
-
Combined hyperthermia and chemotherapy as a synergistic anticancer treatment
Journal of Pharmaceutical Investigation
2019 .01
-
Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk
Immune Network
2023 .10
-
Treatment of Cinnamomi Cortex combined with hyperthermia synergistically suppressed proliferation and induced apoptosis in U937 cell line.
대한한의학방제학회지
2019 .01
-
Current understanding of modulated electro-hyperthermia in cancer treatment
고신대학교 의과대학 학술지
2024 .09
-
Malignant hyperthermia: a case report with a literature review
Archives of Aesthetic Plastic Surgery
2022 .04
-
Current Understanding in Neutrophil Differentiation and Heterogeneity
Immune Network
2017 .10
-
Local Hyperthermia Affects Murine Contact Hypersensitivity around Elicitation Phase
Annals of Dermatology
2018 .01
-
[S3-1] Post-COVID pulmonary injury in K18-hACE mice show persistent neutrophils and neutrophils extracellular trap formation
한국실험동물학회 학술발표대회 논문집
2024 .07
-
Intravital imaging set up of neutrophil extracellular trap in mouse brain to investigate the role of neutrophils in neuroinflammatory diseases
한국실험동물학회 학술발표대회 논문집
2022 .01
-
Baicalein dose-dependently improves testicular injuries induced by scrotal hyperthermia in mice
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Synergistic Anticancer Effect of the Cinnamomi Cortex Ethanol Extract (CcEE) and Hyperthermia in AGS Human Gastric Cancer Cells
대한한의학방제학회지
2019 .01
-
뇌교 출혈 이후 발생한 지연된 중추성 고체온증에 대한 한방치료 1례
대한한방내과학회지
2018 .01
-
Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation
Immune Network
2021 .04
-
Drug-induced Hyperthermic Syndromes in Psychiatry
Clinical Psychopharmacology and Neuroscience
2021 .01
-
Extracellular Vesicles of Neutrophils
Immune Network
2018 .12
-
Prospective phase II trial of regional hyperthermia and whole liver irradiation for numerous chemorefractory liver metastases from colorectal cancer
Radiation oncology journal : ROJ
2016 .01
-
고주파 온열치료와 소라페닙을 병용하여 호전된 재발성 간암환자 1례
대한암한의학회지
2016 .01
-
Current Understanding on the Metabolism of Neutrophils
Immune Network
2020 .12
-
Autophagy in neutrophils
The Korean Journal of Physiology & Pharmacology
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0