지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제18권 제4호
- 발행연도
- 2020.1
- 수록면
- 636 - 640 (5page)
이용수
초록· 키워드
오류제보하기
Psychiatric symptoms are common after traumatic brain injury (TBI), and some patients have poor drug therapeutic efficacy. We report a successfully treated case of psychiatric symptoms after TBI using deep brain stimulation (DBS) to the anterior limb of internal capsule (ALIC)-nucleus accumbens (NAc) in a 76-year-old woman. The patient suffered from auditory hallucination, mood changes, and insomnia caused by TBI. Psychological test assessment showed the scores of Hamilton Anxiety Scale, Hamilton Depression Scale and Positive and Negative Syndrome Scale were 30, 35, and 96 respectively. Head magnetic resonance imaging scan showed right temporal lobe encephalomalacia. Head magnetic resonance spectroscopy (MRS) showed bilateral basal ganglia choline increased relatively. After DBS to the ALIC-NAc, the target parameters were adjusted. The psychiatric symptoms were completely improved and the result of head MRS was normal in the end. The current report declares that DBS is reversible, adjustable and safe in the treatment of psychiatric symptoms caused by TBI. DBS to the ALIC-NAc should be considered as a possible treatment choice once a patient showed psychiatric symptoms after TBI.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
McGuire JL / 2019 / Neurotransmitter changes after traumatic brain injury : an update for new treatment strategies / Mol Psychiatry 24:995~1012
Auxéméry Y / 2012 / Mild traumatic brain injury and postconcussive syndrome : a re-emergent questioning / Encephale 38:329~335
Awwad HO / 2018 / Post-blast treatment with Nociceptin/Orphanin FQ peptide(NOP)receptor antagonist reduces brain injuryinduced hypoxia and signaling proteins in vestibulomotor-related brain regions / Behav Brain Res 340:183~194
Domnick NK / 2015 / Neonatal hypoxia-ischemia impairs juvenile recognition memory by disrupting the maturation of prefrontal-hippocampal networks / Exp Neurol 273:202~214
Albrecht JS / 2017 / Psychotropic medication use among medicare beneficiaries following traumatic brain injury / Am J Geriatr Psychiatry 25:415~424
Auxéméry Y / 2012 / Mild traumatic brain injury and postconcussive syndrome : a re-emergent questioning / Encephale 38:329~335
Awwad HO / 2018 / Post-blast treatment with Nociceptin/Orphanin FQ peptide(NOP)receptor antagonist reduces brain injuryinduced hypoxia and signaling proteins in vestibulomotor-related brain regions / Behav Brain Res 340:183~194
Domnick NK / 2015 / Neonatal hypoxia-ischemia impairs juvenile recognition memory by disrupting the maturation of prefrontal-hippocampal networks / Exp Neurol 273:202~214
Albrecht JS / 2017 / Psychotropic medication use among medicare beneficiaries following traumatic brain injury / Am J Geriatr Psychiatry 25:415~424
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