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논문 기본 정보

자료유형
학술저널
저자정보
Young Jun Park (Department of Family Medicine Seoul National University Hospital Seoul National University College) Yu Jin Cho (Department of Family Medicine Seoul National University Hospital Seoul National University College) Jinseul Kwak (Department of Biomedical Engineering Seoul National University College of Medicine Seoul Korea) Youn-Hee Lim (Section of Environmental Health Department of Public Health Faculty of Health and Medical Sciences) Minseon Park (Department of Family Medicine Seoul National University Hospital Seoul National University College)
저널정보
대한가정의학회 Korean Journal of Family Medicine Korean Journal of Family Medicine 제42권 제4호
발행연도
2021.1
수록면
310 - 316 (7page)

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Background: In hemodialysis patients, brachial-ankle pulse wave velocity (baPWV) levels are affected by particulate matter with an aerodynamic diameter of 10 μm or less (PM10). We conducted this study to determine whether there is an association between short- and long-term PM10 exposure and baPWV in apparently healthy adults aged 40 years and older. Methods: A total of 1,628 subjects who underwent health examinations between 2006 and 2009 were included in the study. On the basis of the day of medical screening, the 1?3-day and 365-day moving averages of PM10 concentrations were used to evaluate the association between short- and long-term exposure to PM10 and high baPWV (≥the third quartile of baPWV, 1,534 cm/s) using logistic regression models. Additional subgroup analyses were conducted according to age, sex, obesity (body mass index ≥25.0 kg/m2), and comorbidities such as metabolic syndrome. Results: No statistically significant associations were identified between short-term and long-term exposure to PM10 and baPWV in any of the subjects and subgroups. A 10-μg/m3 increase in the 2-day moving average of PM10 exposure was marginally associated with high baPWV in non-obese subjects (odds ratio, 1.059; P=0.058). This association in non-obese subjects was significantly different from that in obese subjects (P=0.038). Conclusion: This study did not show statistically significant associations between short-term and long-term exposure to PM10 and baPWV in apparently healthy subjects. With short-term exposure to PM10, non-obese subjects showed a marginally unfavorable association with baPWV. Further studies are necessary to validate and elucidate the mechanism underlying the effect of PM10 on baPWV.

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