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- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 167 - 167 (1page)
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Venous insufficiency results from several factors responsible for the progression of inflammation and oxidative damage of veins. Recently, natural extracts have been proposed for the treatment of venous insufficiency, but their efficacies have not been fully elucidated. In the present study, we evaluate the combinatorial effects on anti-inflammatory and anti-vascular leakage potential of mixed compositions containing different proportions of Centella asiatica extracts (CE) and Vitis vinifera L. leaf extracts (VVE) using an inflammation model of lipopolysaccharide (LPS)-stimulated RAW264.7 cells and various vascular permeability models in mice (acetic acid-induced peritoneal vascular model, mustard oil-stimulated ear vascular model, and carrageenan-induced paw edema model). Pretreatment of CE and VVE in a 1:3 combination dose-dependently inhibited the production of n ... 전체 초록 보기
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