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- 학술대회자료
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- 한국수산과학회 양식분과 한국수산과학회 양식분과 학술대회 2021 Conference on the Future Technology of Fisheries Science [3개 분과 공동개최]
- 발행연도
- 2021.4
- 수록면
- 229 - 229 (1page)
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The coxsackie and adenovirus receptor (CXADR) is an associate of the immunoglobulin family and essential multifunctional cellular protein. Amphiprion clarkii is an ornamental fish in commercial aquaculture. AcCXADR gene was identified from A.clarkii transcriptomic database and characterized. AcCXADR protein consists of 375 amino acids which have a molecular weight of 40.71 kDa with 8.51 of an isoelectric point. AcCXADR is a Type-I transmembrane protein comprised of an N-terminal signal peptide, Ig domain with an extracellular domain containing a V and C2 Ig loop. AcCXADR is strongly and highly expressed in the gills, brain, kidney and liver. As the first line of defence gill is harbouring a higher infection rate and as a vital organ brain and neuron development needed CXADR protein. The immune challenge experiment was disclosed significant upregulation of AcCXADR protein with Vibrio harveyi in the head kidney until 12 p:i then reduced the expression at 24 p:I, and increment of expression occurred in further time points. In the head kidney, after LPS treatment, the expression of protein significantly increases until 12 p:i and gradually reduced to 24-72 ... 전체 초록 보기
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UCI(KEPA) : I410-ECN-0101-2021-529-001945162