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- 학술대회자료
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- 발행연도
- 2021.4
- 수록면
- 522 - 522 (1page)
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Liver is a lobule structure with the gradient of oxygen by blood flowing central vein, and the area with low oxygen pressure is significantly low despite the high amount of oxygen requirement by hepatocytes [1, 2]. Thus, the liver is vulnerable to hypoxic environment such as hypoxemia or low perfusion, causing hypoxic hepatitis (HH) [3]. Furthermore, HH is associated with renal disease and it can further exacerbate renal disease [4]. Therefore, it is critical to develop a model to investigate liver and kidney interaction in hypoxia-induced conditions. In this study, the microfluidic device is used to keep hypoxia condition and to connect two different tissues. The oxygen gas i ... 전체 초록 보기
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