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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.12
- 수록면
- 81 - 90 (10page)
이용수
초록· 키워드
오류제보하기
Sialic acid, which is contained in about 60-160 mg/kg in the edible bird’s nest(EBN), is known to facilitate in the proper formation of synapses and improve memory function. The objective of this study is to extract effectively the sialic acid from edible bird’s nest using affinity bead technology (ABT). After preparing the non-polar polymeric bead “KJM-278-28A” having a porous network structure, and then desorbed sialic acid was concentrated and dried. The analysis of the physicochemical properties of bead “KJM-278-28A” showed that the particle size was 400-700 μm, the moisture holding capacity was 67-70%, the surface area (BET) was 705-900 m²/g, and the average pore diameter 70-87 Å. The adsorption capacity of the bead “KJM-278-28A” for sialic acid was shown a strong physical force to bind sialic acid to the bead surface of 400 mg/L. In addition, as a result of analyzing the adsorption and desorption effects of sialic acid on water, ethanol, and 10% ethanol on the bead, it was confirmed that desorption effectively occurs from the beads when only ethanol is used. As a result of HPLC measurement of the separated sialic acid solution, a total of four sialic acid peaks of N-acetyl-neuraminic acid (Neu5Ac), α,β-anomer of Neu5Ac and N-glycoly-neuraminic acid were identified. Through these results, it was confirmed that it is possible to separate sialic acid from EBN extract with efficient and high yield when using ABT.
목차
Abstract
1. 서론
2. 재료 및 방법
3. 결과 및 고찰
References
참고문헌 (32)
참고문헌 신청
Chantler, P / 2010 / Swifts: a guide to the swifts and treeswifts of the world / Pica Press :150~152
Matsukawa, N. / 2011 / Improve ment of bone strength and dermal thickness due to dietary edible bird’s nest extract in ovariectomized rats / Biosci. Biotechnol. Biochem 75:590~592
Marni, S. / 2014 / Preliminary study on free sialic acid content of edible bird nest from johor and kela ntan / MJVR 5:9~14
Careena, S. / 2018 / Effect of edible bird’s nest extract on lipopolysaccharide-induced impairm ent of learning and memory in wistar rats / Evid. Based Complementary Altern. Med 18:1~7
Colombo, J. P. / 2003 / Potential effects of supplementation with amino aci ds, choline or sialic acid on cognitive development in you ng infants / Acta Paediatr 92:42~46
Matsukawa, N. / 2011 / Improve ment of bone strength and dermal thickness due to dietary edible bird’s nest extract in ovariectomized rats / Biosci. Biotechnol. Biochem 75:590~592
Marni, S. / 2014 / Preliminary study on free sialic acid content of edible bird nest from johor and kela ntan / MJVR 5:9~14
Careena, S. / 2018 / Effect of edible bird’s nest extract on lipopolysaccharide-induced impairm ent of learning and memory in wistar rats / Evid. Based Complementary Altern. Med 18:1~7
Colombo, J. P. / 2003 / Potential effects of supplementation with amino aci ds, choline or sialic acid on cognitive development in you ng infants / Acta Paediatr 92:42~46
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