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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국식품영양과학회 Preventive Nutrition and Food Science Preventive Nutrition and Food Science Vol.25 No.4
- 발행연도
- 2020.12
- 수록면
- 325 - 337 (13page)
- DOI
- 10.3746/pnf.2020.25.4.325
이용수
초록· 키워드
오류제보하기
A healthy diet has long been indicated to be protective against Alzheimer’s diseases (AD). We carried out a systematic review and meta-analysis of published observational studies to explore the relationship between healthy and unhealthy diets and risk of ADs. We screened PubMed, Scopus, Web of Sciences, Google Scholar, Science Direct, and Embase, and screened manually to identify relevant articles published in English and non-English until Jun 2020. We classified the studied dietary patterns into two groups: healthy and unhealthy diets. The pooled weighted mean difference and 95% confidence interval (95% CI) was used to analyze the data using a random-effects model. The data were extracted manually and the preferred reporting items for systematic review and meta-analysis checklist was used to appraise the risk of bias and quality of data. Of the 1,813 articles identified, 21 met the inclusion criteria and were included in the quantitative analysis. A healthy diet was related to a lower risk of AD [odds ratio (OR): 0.45, 95% CI: 0.23 to 0.86, I2=99.7%; n=17 studies]. Moreover, high adherence to an unhealthy diet was not associated with increased risk of AD (OR: 0.99, 95% CI: 0.98 to 0.99, I2=0.0%; n=6 studies). However, the etiology of AD is uncertain and it is difficult draw conclusions about dietary healthy patterns. We concluded that adherence to a healthy diet is associated with a lower risk of AD, but were unable to find evidence that an unhealthy diet increases the risk of AD.
목차
ABSTRACT
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISSCUSION
REFERENCES
참고문헌 (56)
참고문헌 신청
Alzheimer’s Association / 2015 / Alzheimer’s disease facts and figures / Alzheimers Dement 11:332~384
Berti V / 2015 / Nutrient patterns and brain biomarkers of Alzheimer’s disease in cognitively normal individuals / J Nutr Health Aging 19:413~423
Brookmeyer R / 2018 / Forecasting the prevalence of preclinical and clinical Alzheimer’s disease in the United States / Alzheimers Dement 14:121~129
Calil SRB / 2018 / Adherence to the Mediterranean and MIND diets is associated with better cognition in healthy seniors but not in MCI or AD / Clin Nutr ESPEN 28:201~207
Cox LM / 2019 / Calorie restriction slows age-related microbiota changes in an Alzheimer’s disease model in female mice / Sci Rep 9:17904
Berti V / 2015 / Nutrient patterns and brain biomarkers of Alzheimer’s disease in cognitively normal individuals / J Nutr Health Aging 19:413~423
Brookmeyer R / 2018 / Forecasting the prevalence of preclinical and clinical Alzheimer’s disease in the United States / Alzheimers Dement 14:121~129
Calil SRB / 2018 / Adherence to the Mediterranean and MIND diets is associated with better cognition in healthy seniors but not in MCI or AD / Clin Nutr ESPEN 28:201~207
Cox LM / 2019 / Calorie restriction slows age-related microbiota changes in an Alzheimer’s disease model in female mice / Sci Rep 9:17904
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