지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국농약과학회 농약과학회지 농약과학회지 제24권 제4호
- 발행연도
- 2020.12
- 수록면
- 343 - 351 (9page)
- DOI
- 10.7585/kjps.2020.24.4.343
이용수
이 논문의 연구 히스토리 (5)
2021
2020
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Phosmet, an organophosphate pesticide, has been widely applied to plants and animals. As the adverse effects of phosmet on the aquatic vertebrates are not fully understood, the present study was aimed to evaluate the developmental toxicity of phosmet u sing zebrafish (ZF) (Danio rerio) embryos. The ZF embryos were treated with 2.96, 4.44, 6.66, 10, and 15 mg/L of phosmet. Consequently, the embryo mortalities and developmental deformities were recorded at 24, 48, 72, and 96 hours post fertilization (hpf). The results showed that the effects of phosmet on ZF embryos were time- and dose-dependent. The median lethal concentration (LC₅₀) of phosmet at 96 h was 7.95 ± 0.30 mg/L. The results of developmental toxicity showed that the phosmet induced a series of deformities in somites, tails, spines, yolk-sacs, hearts and swim bladders of ZF embryos and larvae. Among the deformities, the heart- and growth-related deformities were the most significant. Further, the phosmet-treated ZF displayed an abnormal touch-evoked response and swimming, suggesting potential neurodevelopmental toxicity of phosmet. The median effective concentration (EC₅₀) of phosmet at 96 h was 4.38 ± 0.18 mg/L and the 96 h teratogenic index (TI) value was 1.7. Overall, these results indicate that phosmet is a teratogen and severely affects the growth of ZF in the earlier developmental stages.
목차
Abstract
Introduction
Materials and methods
Results and Discussion
Literature cited
참고문헌 (38)
참고문헌 신청
Behra M / 2002 / Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo / Nat. Neurosci 5(2):111~118
Bleyl DW / 1980 / Embryotoxicity and teratogenicity of phosmet in mice / Arch. Exp. Veterinarmed 34(5):791~795
Braida D / 2014 / Role of neuronal nicotinic acetylcholine receptors(nAChRs)on learning and memory in zebrafish / Psychopharmacol 231(9):1975~1985
Busquet F / 2014 / OECD validation study to assess intra-and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing / Regul. Toxicol. Pharmacol 69(3):496~511
Cao F / 2018 / Biological impacts of organophosphates chlorpyrifos and diazinon on development, mitochondrial bioenergetics, and locomotor activity in zebrafish(Danio rerio) / Neurotoxicol. Teratol 70:18~27
Bleyl DW / 1980 / Embryotoxicity and teratogenicity of phosmet in mice / Arch. Exp. Veterinarmed 34(5):791~795
Braida D / 2014 / Role of neuronal nicotinic acetylcholine receptors(nAChRs)on learning and memory in zebrafish / Psychopharmacol 231(9):1975~1985
Busquet F / 2014 / OECD validation study to assess intra-and inter-laboratory reproducibility of the zebrafish embryo toxicity test for acute aquatic toxicity testing / Regul. Toxicol. Pharmacol 69(3):496~511
Cao F / 2018 / Biological impacts of organophosphates chlorpyrifos and diazinon on development, mitochondrial bioenergetics, and locomotor activity in zebrafish(Danio rerio) / Neurotoxicol. Teratol 70:18~27
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Effects of phosmet on normal growth and cardiac function of Zebrafish (Danio rerio) embryos
한국농약과학회 학술발표대회 논문집
2020 .11
-
Total particulate matter from urban aerosols induces developmental toxicity in zebrafish (Danio rerio) embryos
한국수산과학회 양식분과 학술대회
2021 .04
-
Toxicity assessment of rotenone at different embryonic stages of zebrafish
한국수산과학회 양식분과 학술대회
2021 .04
-
Toxicological evaluation of organic contaminants in aquatic system using zebrafish embryo
한국농약과학회 학술발표대회 논문집
2021 .11
-
Comparison of Embryo Culture Efficiency in Early Maturing Peach (Prunus persica) according to Developmental Stages of Embryo and Medium Composition
한국원예학회 학술발표요지
2023 .10
-
Sex ratio and conception rates of fresh / vitrified embryos at different developmental stages by ovum pick up in Hanwoo cows
한국축산학회지
2024 .09
-
Cysteine 첨가로 배양된 소 수정란의 발달과 동결성 효과
한국수정란이식학회지
2016 .01
-
제브라피쉬(Danio rerio)를 이용한 비소 고함류 3종 해조류 추출물의 급성 독성평가
한국수산과학회지
2018 .02
-
Follistatins have potential functional role in Porcine Embryogenesis
Korean Journal of Agricultural Science
2016 .03
-
Role of moss and Arabidopsis zinc-finger homeodomain transcription factors in regulating plant architecture
Plant Biotechnology Reports
2024 .04
-
Reproductive toxicity of thiram to zebrafish (Danio rerio)
한국농약과학회 학술발표대회 논문집
2021 .05
-
후대의 육질등급이 우수한 한우 암소의 수정란 생산 및 이식에 관한 연구
한국동물생명공학회지
2019 .01
-
Zebrafish Embryo를 이용한 작물보호제의 위해성평가 사례에 대한 고찰
한국농약과학회 학술발표대회 논문집
2025 .04
-
Prospects of Embryo Rescue in Developing Novel Brassica Genotypes
Plant Breeding and Biotechnology
2023 .03
-
Combined Toxicities of Endosulfan with Phenanthrene against Zebrafish Adults (Danio rerio)
한국농약과학회 학술발표대회 논문집
2017 .04
-
개 parthenote in vitro culture시 EDTA 첨가에 의한 발달율 향상
한국수정란이식학회지
2018 .01
-
Long arm octopus (Octopus minor) extract prevents eye injury caused by particulate matter exposure in zebrafish (Danio rerio) embryos
Fisheries and Aquatic Sciences
2024 .02
-
Effect of OPU Session Periods on the Efficiency of In Vitro Embryo Production in Elite Korean Native Cow
한국수정란이식학회지
2018 .01
-
A marine algal polyphenol inhibits high-glucose induced oxidative stress in zebrafish embryos
한국수산과학회 양식분과 학술대회
2019 .05
-
배아추출물 공여 배아의 발생단계가 바다송사리(Oryzias dancena) 배아 줄기세포 유사세포의 배양에 미치는 영향
한국수산과학회지
2017 .04
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2021-523-000068711