지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한약학회 Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea 제30권 제3호
- 발행연도
- 2007.1
- 수록면
- 313 - 316 (4page)
이용수
초록· 키워드
오류제보하기
Licochalcones A (1) and E (2), retrochalcones or reversely constructed chalcones, isolated from the roots of Glycyrrhiza inflate, were evaluated for their cytotoxicities against four different human tumor cell lines; A549 (lung), SK-OV-3 (ovarian), SK-MEL-2 (melanoma) and HCT-15 (colon), using the sulforhodamine B (SRB) assay. The effects of these compounds toward the DNA topoisomerase I (tope I) inhibitory of activity were also measured using the supercoiled DNA unwinding assay. All compounds showed moderate cytotoxicities against the four different human tumor cell lines and inhibited the tope I activity in dose-dependent manners. The inhibition of topo I by licochalcones A (1) and E (2) may explain the cytotoxicities of these compounds against the human tumor cell lines.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Licochalcone A가 대식세포주의 사이토카인 생성에 미치는 영향
약학회지
2009 .01
-
Improved cytotoxicity of DA-125 through high-affinity DNA binding and potent inhibition of Topoisomerase II activity
대한약학회 학술대회
2001 .01
-
Synthesis, Biological Activity and Comparative Analysis of Cytotoxicities and Human Topoisomerase I Inhibitory Activities of Isoquinoline Compounds
대한약학회 학술대회
2001 .01
-
Cytotoxicity and DNA Topoisomerase Inhibitory Activity of Constituents Isolated from the Fruits of Evodia officinalis
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2006 .01
-
Cytotoxic and DNA Topoisomerases I and II Inhibitory Constituents from the Roots of Aralia cordata
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Cytotoxicity and DNA Topoisomerases Inhibitory Activity of Constituents from the Sclerotium of Poria cocos
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
Licochalcone Suppresses LXRα-Induced Hepatic Lipogenic Gene Expression through AMPK/Sirt1 Pathway Activation
Toxicological Research
2014 .03
-
퀴놀론 유도체의 Topoisomerase II에 대한 효과
약학회지
1996 .01
-
Topoisomerase I and II Inhibitory Constituents from the Bark of Tilia amurensis
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
-
Inhibition of Topoisomerase I Activity and Efflux Drug Transporters' Expression by Xanthohumol from Hops
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2007 .01
-
Synthesis and In Vitro Cytotoxicity of Cinnamaldehydes to Hyman Solid Tumor Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1998 .01
-
Licochalcone A, a Major Phenolic Constituent of Glycyrrhiza inflata, Suppresses Angiogenin Expression in Colon Cancer Cells
대한의생명과학회지
2011 .03
-
Synthesis of New 3-Arylisoquinolinamines: Effect on Topoisomerase I Inhibition and Cytotoxicity
대한약학회 학술대회
2003 .01
-
6-(1-하이드록시 또는 아실옥시알킬)-5,8-디알콕시-1,4-나프토퀴논 유도체의 합성, DNA Topoisomerase-I에 대한 억제, 세포독성 및 항암활성
약학회지
2000 .01
-
Da-125 a New Antitumor Agent, Inhibits Topoisomerase II as Topoisomerase Poison and DNA Intercalator Simultaneously
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
-
DNA Topoisomerases I and II Inhibitory Activity of Constituents Isolated from Juglans mandshurica
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2003 .01
-
자외선을 조사한 포유동물 세포에 있어 DNA회복에 미치는 Topoisomerase II의 역할 ( The Roles of Topoisomerase II on DNA Repair in UV-Irradiated Mammalian Cells )
한국환경성돌연변이·발암원학회지
1986 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0