지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 204 - 208 (5page)
이용수
초록· 키워드
오류제보하기
Chaga mushroom extract is well known as immune modulator and anti-cancer agent. However, the molecular mechanism by which Chaga exerts cell cycle arrest and apoptosis of cancer cells is poorly understood. In this study, we demonstrated anti-proliferative effects of Chaga extract on murine melanoma B16 cells. Chaga extract dose-dependently inhibited cell growth along with the arrest of G0/G1 phase and the induction of apoptotic cell death. Treatment with Chaga extract resulted in a decrease of cyclin E, cyclin D1, cdk 2, cdk 4 expression levels. Furthermore, in vivo inoculation study of B16 melanoma cells into Balb/c mice Chaga extract markedly suppressed the metastatic growth of tumor cells (6 folds, p<0.05,). These results indicate that Chaga mushroom extract induces apoptosis of B16 melanoma cells through arrest of G0/G1 phase in cell cycle.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
차가버섯추출물에 의한 흑색종의 세포주기 억제효과
동의생리병리학회지
2007 .02
-
Comparative Studies to Evaluate Relative in vitro Potency of Luteolin in Inducing Cell Cycle Arrest and Apoptosis in HaCaT and A375 Cells
Asian Pacific journal of cancer prevention : APJCP
2013 .01
-
S Phase Cell Cycle Arrest and Apoptosis is Induced by Eugenol in G361 Human Melanoma Cells
International Journal of Oral Biology
2011 .01
-
Urushiol Induced Apoptosis and Cell Cycle Arrest in Human Gastric Cancer Cells
대한약학회 학술대회
2001 .01
-
The Cytotoxic Effect of Chaga Mushroom (Inonotus Obliquus) Water Extract on HepG2 Hepatoma Cells
대한의생명과학회지
2011 .09
-
New HDAC inhibitor, IN2001 induces apoptosis/cell cycle arrest in human breast cancer cells
환경독성보건학회 심포지엄 및 학술대회
2003 .10
-
차가버섯 열수 추출물이 비장세포 증식능과 Cytokine 생성능에 미치는 영향
약학회지
2010 .01
-
Cadmium Induces Cell Cycle Arrest and Change in Expression of Cell Cycle Related Proteins in Breast Cancer Cell Lines
Toxicological Research
2005 .03
-
Small Cell Melanoma
Annals of Dermatology
2014 .01
-
Cell Cycle, Cell Death and Apoptosis
대한핵의학회 연수교육
2002 .01
-
Methylmercury induced cell cycle arrest but not apoptosis by mechanism independent of p53 in Nerve Differentiation Phase
환경독성보건학회 심포지엄 및 학술대회
2005 .11
-
Methylmercury induced cell cycle arrest but not apoptosis by Mechanism independent of p53 in Nerve Differentiation Phase
환경독성보건학회 심포지엄 및 학술대회
2005 .05
-
Bracken-fern Extracts Induce Cell Cycle Arrest and Apoptosis in Certain Cancer Cell Lines
Asian Pacific journal of cancer prevention : APJCP
2012 .01
-
High-Dose $^{111}In$ Induces G1 Cell Cycle Arrest and Cell Death in Rat Bone Marrow Mesenchymal Stem Cells
Nuclear medicine and molecular imaging : NMMI
2012 .01
-
인체 흑색종 세포에 대한 와송 추출물의 세포주기 억제를 통한 항암효과와 기전 연구
한방안이비인후피부과학회지
2019 .01
-
Celecoxib, a COX-2 Selective Inhibitor, Induces Cell Cycle Arrest at the G2/M Phase in HeLa Cervical Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
Radiation-induced Apoptosis, Necrosis and G2 Arrest in Fadu and Hep2 Cells
대한구강악안면방사선학회지
2000 .01
-
Radical Intermediate Generation and Cell Cycle Arrest by an Aqueous Extract of Thunbergia Laurifolia Linn. in Human Breast Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
청국장에서 얻은 Isoflavone의 MDA-MB-453세포에서 항암효과 및 관련 기전
약학회지
2014 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0