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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.1
- 수록면
- 254 - 261 (8page)
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초록· 키워드
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20-O-($\beta$-D-Glucopyranosyl)-20 (S)-protopanaxadiol (IH-901) is one of the major metabolites of ginsenosides from Panax ginseng, and is suggested that IH-901 has been associated with various pharmacological and physiological activities. In this study, we demonstrate that IH-901 induced anti-inflammation in HT-29 human colon adenocarcinoma cells. Our results showed that IH-901 inhibited cell proliferation of HT-29 in a time- and dose-dependent manner. We also found that IH-901 was significantly decreased expression of iNOS compared with non-treated. We observed effect of IH-901 related with inflammatory genes using by cDNA microarray. We were known that the 34 inflammatory genes such as E2F, CDK6, TNF-$\alpha$, and PKC were down-regulated. Thus, these results suggest that IH-901 may have a potential preventive factor to improving cancer induced by chronic inflammation.
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In vitro antioxidant properties of a ginseng intestinal metabolite IH-901
Laboratory Animal Research
2011 .09
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db/db 마우스에서 IH-901의 항 당뇨 활성
약학회지
2006 .01
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General Pharmacology of IH-901
The journal of applied pharmacology : the official journal of the Korean Society of Applied Pharmacology
2003 .01
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A Study on the Anti-metastatic activities and Toxicity of IH-901
대한약학회 학술대회
2000 .01
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Kinetic Analysis of the Hepatic Uptake and Biliary Excretion of IH-901. a Potential Anticancer Agents. in Rats
대한약학회 학술대회
2002 .01
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Role of the Fas/Fas Ligand Death Receptor Pathway in Ginseng Saponin Metabolite-Induced Apoptosis in HepG2 Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2004 .01
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Comparative Analysis of the Extracellular Matrix Composition in Proliferating and Involuted Infantile Hemangiomas
Archives of plastic surgery : APS
2015 .01
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Streptozotocin 유발 당뇨 흰쥐에서 백삼 에탄올엑스와 IH-901의 항당뇨 작용 비교
약학회지
2003 .01
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In vitro antioxidant properties of ginseng intestinal metabolite (IH901)
한국실험동물학회 학술발표대회 논문집
2008 .11
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A ginseng saponin metabolite-induced apoptosis in HepG2 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and Bid cleavage
대한약학회 학술대회
2003 .01
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Radical Scavenging and Reducing Properties of IH901, Ginseng Intestinal Metabolite
한국실험동물학회 학술발표대회 논문집
2009 .04
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An Enzyme-linked Immunosorbent for IH-901, an Active Metabolite of Ginsenoside Rb1
대한약학회 학술대회
2000 .01
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Congenital Internal Hernia Presented with Life Threatening Extensive Small Bowel Strangulation
Pediatric Gastroenterology, Hepatology & Nutrition
2013 .01
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In vivo antioxidant effects of ginseng intestinal metabolite (IH901) in endurance exercise-induced oxidative stress rat model
한국실험동물학회 학술발표대회 논문집
2008 .11
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Interaction of IH901 and Physical Stress on Antioxidant Defense System in Skeletal Muscle and Lung Tissue of Rat
한국실험동물학회 학술발표대회 논문집
2009 .04
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Antitumor and Cardioprotective Effects of a Ginseng Intestinal Metabolite in Combination with Doxorubicin in Sarcoma-180 Tumor-bearing Mice
Laboratory Animal Research
2004 .12
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Comparisons of antidiabetic activity between ethanol extract of white ginseng root and IH901 in streptozotocin-induced diabetic rats
대한약학회 학술대회
2002 .01
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Establishment of an ELISA for the Determination of IH-901 Using the Antibody against Ginsenoside Re-Bovine Serum Albumin conjugate
대한약학회 학술대회
2001 .01
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