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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 뮤코다당증연구학회 Journal of mucopolysaccharidosis and rare disease Journal of mucopolysaccharidosis and rare disease 제1권 제1호
- 발행연도
- 2015.1
- 수록면
- 28 - 30 (3page)
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초록· 키워드
오류제보하기
Biologics present a challenge to both the manufacturer and end user. They must usually be formulated as parenterals. However, they are often unstable in liquid form, due to their complex structure and composition. In that case, they must be manufactured using highly specialized processes, such as lyophilization (freeze-drying). Lyophilization nearly eliminates stability issues. Reducing a compound's sensitivity to temperature prolongs its shelf life. However, reconstitution can be cumbersome, involving multiple steps that increase the potential for error. Dual-chamber technology provides an effective alternative, combining a lyophilized drug and diluent in a closed system and enabling reconstitution in a few simple steps.
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