지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 272 - 277 (6page)
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초록· 키워드
오류제보하기
Background One-per-mil tumescent solution, which contains 0.2% lidocaine with 1:1,000,000 epinephrine, has been reported to be clinically effective for hand surgery under local anesthesia. However, it was lacking in its basic pharmacokinetics profile in regard to the onset of action (OOA) and duration of action (DOA). Methods A randomized, double-blind study was conducted on 12 volunteers who met the inclusion criteria from October to November 2014. All volunteers had their right and left ring finger pulps injected with either one-per-mil solution or 2% lidocaine. Semmes-Weinstein and two-point discrimination tests were used to test sensation. Visual analogue scale was recorded at the time when the finger lost its sensation and when it regained normal sensation to measure the OOA and DOA. The data were then analyzed with a paired t-test and a Wilcoxon signed-rank test. Results The OOA and DOA of 2% plain lidocaine were 1 minute and 99.67 minutes, respectively. Meanwhile, 0.2% lidocaine in a one-per-mil tumescent solution showed an OOA of 5 minutes and a DOA of 186.83 minutes. The OOA of 0.2% lidocaine in a one-per-mil tumescent solution is statistically shorter than 2% plain lidocaine (P=0.04); while its DOA is statistically longer than 2% plain lidocaine (P<0.001). Conclusions The 0.2% lidocaine in a one-per-mil tumescent solution is statistically and clinically superior to 2% plain lidocaine in achieving longer duration of local anesthesia.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Tzeng YS / 2012 / Tumescent technique in digits: a subcutaneous single-injection digital block / Am J Emerg Med 30:592~596
Thomson CJ / 2006 / Randomized double-blind comparison of duration of anesthesia among three commonly used agents in digital nerve block / Plast Reconstr Surg 118:429~432
McLure HA / 2005 / Review of local anaesthetic agents / Minerva Anestesiol 71:59~74
Calder K / 2013 / Bupivacaine digital blocks: how long is the pain relief and temperature elevation? / Plast Reconstr Surg 131:1098~1104
Rubin JP / 2005 / Rapid absorption of tumescent lidocaine above the clavicles: a prospective clinical study / Plast Reconstr Surg 115:1744~1751
Thomson CJ / 2006 / Randomized double-blind comparison of duration of anesthesia among three commonly used agents in digital nerve block / Plast Reconstr Surg 118:429~432
McLure HA / 2005 / Review of local anaesthetic agents / Minerva Anestesiol 71:59~74
Calder K / 2013 / Bupivacaine digital blocks: how long is the pain relief and temperature elevation? / Plast Reconstr Surg 131:1098~1104
Rubin JP / 2005 / Rapid absorption of tumescent lidocaine above the clavicles: a prospective clinical study / Plast Reconstr Surg 115:1744~1751
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