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논문 기본 정보

자료유형
학술저널
저자정보
Choi, Jung-Hyun (Namseoul University) Kim, Sung-Won (Dongnam Health College) Lee, Jae-Gap (Hallym University Sacred Heart Hospital) Kim, Min-Hee (Hallym University Sacred Heart Hospital) Kim, Ji-Sung (Suwon Women's College) Choi, Yoo-Rim (Daegu Science College) Yun, Young-Dae (Yonsei Semirae Hospital) Kim, Chi-Hyok (Kyungnam College of Technology) Kim, Yong-Seong (St. Vincent's Hospital) Kim, Nyeon-Jun (Pohang College) Lee, Ju-Hwan (The Armed Forces Capital Hospital) Lee, Sang-Bin (Namseoul University)
저널정보
국제물리치료연구학회 Journal of international academy of physical therapy research Journal of international academy of physical therapy research 제1권 제2호
발행연도
2010.1
수록면
136 - 142 (7page)

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This study aims to reveal how EA affects BAX and NF-kB involved in cell deaths from global ischemia, and to do this, observes the changes of BAX and NF-kB caused by EA application after transient global ischemia. The experimental method is to give rise to global ischemia and apply EA to 27 SD rats with the particulars of being six-week-old, male, around-300 gram-weighing, and adapted to laboratory environment for more than a week, and divide them into three groups, that is, GV20 EA group(n=9), L14 EA group(n=9), no-treatment GI group(n=9), and then observe their changes of BAX and NF-kB at the time lapse of 6 hours, 9 hours and 12 hours after ischemia, using western blotting. The numerical decrease of BAX expression at the time lapse of 9 hours after EA application, though not statistically significant, was observed in GV20 EA group and L14 EA group, and the NF-kB expression appeared statistically significant decrease in GV20 EA group and L14 EA group, but the expression was higher in the group with EA application. Therefore, EA application at the early phase of global ischemia is considered to affect BAX and NF-kB and play a positive role in decreasing apoptosis and cell deaths by inflammation.

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