지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 73 - 78 (6page)
이용수
초록· 키워드
오류제보하기
Toll-like receptors (TLRs) play an important role in initiating innate immune responses. The stimulation of TLRs by microbial components triggers the activation of two downstream signaling pathways: myeloid differential factor 88 (MyD88)- and toll-interleukin-1 receptor domain-containing adapter inducing interferon-$\beta$ (TRIF)-dependent signaling pathways. Wood vinegar (WV), a byproduct from charcoal production, has been evaluated for its various biological activities including anti-oxidant, anti-bacterial, and anti-inflammatory activities. To evaluate the therapeutic potential of WV, we examined its effect on signal transduction via the TRIF-dependent pathway of TLRs induced by TLR3 and TLR4 agonists. Oak wood vinegar (OWV) inhibited nuclear factor-$\kappa$B and interferon regulatory factor 3 activation induced by lipopolysaccharide(LPS) or polyinosinic-polycytidylic acid (poly [I:C]). OWV also inhibited LPS- or poly[I:C]-induced interferon inducible protein-10(IP-10). These results suggest that OWV can modulate TRIF-dependent signaling pathway of TLRs for anti-viral, anti-bacterial, and anti-inflammatory activities.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Suppression of the TRIF-dependent Signaling Pathway of Toll-like Receptor by Cadmium in RAW264.7 Macrophages
Molecular & cellular toxicology
2009 .01
-
Oak Wood Vinegar Suppresses the Expression of Cyclooxygenase-2 Induced by TLR4 Agonist
대한의생명과학회지
2009 .09
-
Clinical Significance of Toll-Like Receptor and Toll-Like Receptor Blocker
Urogenital Tract Infection
2016 .01
-
Toll-like Receptors and Innate Immunity
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2011 .12
-
The Anti-Inflammatory Effects of Phytochemicals by the Modulation of Innate Immunity
대한의생명과학회지
2012 .09
-
Nucleic Acid Recognition and Signaling by Toll-like Receptor 9
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2011 .06
-
TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling
Yonsei Medical Journal
2018 .01
-
Intrinsic Cellular Defenses against Virus Infection by Antiviral Type I Interferon
Yonsei Medical Journal
2010 .01
-
Triptolide Suppresses the Expression of Cyclooxygenase-2 Induced by Toll-Like Receptor 3 and 4 Agonists
대한의생명과학회지
2013 .06
-
TLR10 and Its Unique Anti-Inflammatory Properties and Potential Use as a Target in Therapeutics
Immune Network
2020 .06
-
Effector Pathways of Toll-like Receptor-inducible Innate Immune Responses in Macrophages
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2019 .03
-
IGF-I Exerts an Anti-inflammatory Effect on Skeletal Muscle Cells through Down-regulation of TLR4 Signaling
Immune Network
2011 .08
-
Cadmium but not Mercury Suppresses NF-$\kappa$B Activation and COX-2 Expression Induced by Toll-like Receptor 2 and 4 Agonists
Molecular & cellular toxicology
2009 .01
-
중이 진주종에서 Toll Like Receptor 2와 4의 발현
대한이비인후-두경부외과학회지
2006 .01
-
적소두 추출물이 톨유사수용체 활성 및 염증유발 사이토카인의 생성에 미치는 영향
동의생리병리학회지
2012 .08
-
Toll-Like Receptor Gene Expression during Trichinella spiralis Infection
Parasites, Hosts and Diseases
2015 .08
-
적소두 추출물이 톨유사수용체 활성 및 염증유발 사이토카인의 생성에 미치는 영향
동의생리병리학회지
2012 .01
-
Dehydrocostus Lactone Suppresses the Expression of iNOS Induced by TLR Agonists
대한의생명과학회지
2019 .09
-
Pristimerin Inhibits Inducible Nitric Oxide Synthase Expression Induced by TLR Agonists
대한의생명과학회지
2019 .03
-
Sex hormones alter the response of Toll-like receptor 3 to its specific ligand in fallopian tube epithelial cells
Clinical and experimental reproductive medicine : CERM
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0