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논문 기본 정보

자료유형
학술저널
저자정보
Lee, Jongmin (Division of Pulmonary, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Kim, Young Kyoon (Division of Pulmonary, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea) Seo, Ye Young (Department of Nuclear Medicine, Inje University Sanggye Paik Hospital) Choi, Eun Kyoung (Department of Radiology, College of Medicine, The Catholic University of Korea) Lee, Dong Soo (Department of Radiation Oncology, College of Medicine, The Catholic University of Korea) Kim, Yeon Sil (Department of Radiation Oncology, College of Medicine, The Catholic University of Korea) Hong, Sook Hee (Division of Medical Oncology, College of Medicine, The Catholic University of Korea) Kang, Jin Hyoung (Division of Medical Oncology, College of Medicine, The Catholic University of Korea) Lee, Kyo Young (Department of Hospital Pathology, College of Medicine, The Catholic University of Korea) Park, Jae Kil (Department of Thoracic Surgery, College of Medicine, The Catholic University of Korea) Sung, Sook Whan (Department of Thoracic Surgery, College) Kim, Hyun Bin Park, Mi Sun Yim, Hyeon Woo Kim, Seung Joon
저널정보
대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제81권 제4호
발행연도
2018.1
수록면
339 - 346 (8page)

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Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a standard procedure to evaluate suspicious lymph node involvement of lung cancer because computed tomography (CT) and $^{18}F$-fluorodeoxyglucose positron emission tomography-CT (PET-CT) have limitations in their sensitivity and specificity. There are a number of benign causes of false positive lymph node such as anthracosis or anthracofibrosis, pneumoconiosis, old or active tuberculosis, interstitial lung disease, and other infectious conditions including pneumonia. The purpose of this study was to evaluate possible causes of false positive lymph node detected in chest CT or PET-CT. Methods: Two hundred forty-seven patients who were initially diagnosed with lung cancer between May 2009 and December 2012, and underwent EBUS-TBNA to confirm suspicious lymph node involvement by chest CT or PET-CT were analyzed for the study. Results: Of 247 cases, EBUS-TBNA confirmed malignancy in at least one lymph node in 189. The remaining 58 patients whose EBUS-TBNA results were negative were analyzed. Age ${\geq}65$, squamous cell carcinoma as the histologic type, and pneumoconiosis were related with false-positive lymph node involvement on imaging studies such as chest CT and PET-CT. Conclusion: These findings suggest that lung cancer staging should be done more carefully when a patient has clinically benign lymph node characteristics including older age, squamous cell carcinoma, and benign lung conditions.

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