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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 216 - 224 (9page)
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Purpose Lymph node metastasis is an important factor for predicting the prognosis of colorectal can- cer patients. However, approximately 60% of patients do not receive adequate lymph node evaluation (less than 12 lymph nodes). In this study, we identified a more effective tool for predicting the prognosis of patients who received inadequate lymph node evaluation.
Materials and Methods The number of metastatic lymph nodes, total number of lymph nodes examined, number of negative metastatic lymph nodes (NL), lymph node ratio (LR), and the number of apical lymph nodes (APL) were examined, and the prognostic impact of these parameters was examined in patients with colorectal cancer who underwent surgery from January 2004 to December 2011. In total, 806 people were analyzed retrospectively.
Results In comparison of different lymph node analysis methods for rectal cancer patients who did not receive adequate lymph node dissection, the LR showed a significant difference in over- all survival (OS) and the APL predicted a significant difference in disease-free survival (DFS).
In the case of colon cancer patients who did not receive adequate lymph node dissection, LR predicted a significant difference in DFS and OS, and the APL predicted a significant difference in DFS.
Conclusion If patients did not receive adequate lymph node evaluation, the LR and NL were useful parameters to complement N stage for predicting OS in colon cancer, whereas LR was com- plementary for rectal cancer. The APL could be used for prediction of DFS in all patients.
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참고문헌 (17)
참고문헌 신청
Townsend CM Jr / 2012 / Sabiston textbook of surgery: the biological basis of modern surgical pra / Elsevier/Saunders
Brunicardi FC / 2010 / Schwartz's principles of surgery / McGraw-Hill Education
Baxter NN / 2005 / Lymph node evaluation in colorectal cancer patients : a population-based study / J Natl Cancer Inst 97:219~225
Chang GJ / 2007 / Lymph node evaluation and survival after curative resection of colon cancer : systematic review / J Natl Cancer Inst 99:433~441
Ogino S / 2010 / Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lymphocytic reaction / Am J Gastroenterol 105:420~433
Brunicardi FC / 2010 / Schwartz's principles of surgery / McGraw-Hill Education
Baxter NN / 2005 / Lymph node evaluation in colorectal cancer patients : a population-based study / J Natl Cancer Inst 97:219~225
Chang GJ / 2007 / Lymph node evaluation and survival after curative resection of colon cancer : systematic review / J Natl Cancer Inst 99:433~441
Ogino S / 2010 / Negative lymph node count is associated with survival of colorectal cancer patients, independent of tumoral molecular alterations and lymphocytic reaction / Am J Gastroenterol 105:420~433
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