지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 1 - 9 (9page)
이용수
초록· 키워드
오류제보하기
In the developing limb, chondrogenesis is an important prerequisite for the formation of cartilage whose template is required for bone formation. Chondrogenesis is a tightly regulated multi-step process, including mesenchymal cell recruitment/migration, prechondrogenic condensation of the mesenchymal cells, commitment to the chondrogenic lineage, and differentiation into chondrocytes. This process is controlled exquisitely by cellular interactions with the surrounding matrix and regulating factors that initiate or suppress cellular signaling pathways and transcription of specific genes in a temporal-spatial manner. Understanding the cellular and molecular mechanisms of chondrogenesis is important not only in the context of establishing basic principle of developmental biology but also in providing research direction toward preventive and/or regenerative medicine. Here, I will overview the current understanding of cellular and molecular mechanisms contributing to prechondrogenic condensation processes, the crucial steps for chondrogenesis, focusing on cell-cell and cell-matrix interactions.
목차
등록된 정보가 없습니다.
참고문헌 (99)
참고문헌 신청
Akiyama H / 2002 / The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6 / Genes 16:2813~2828
Amãlinei C / 2007 / Biology of metalloproteinases / Rom J Morphol Embryol 48:323~334
Aulthouse AL / 1987 / The detection of a precartilage, blastema-specific marker / Dev Biol 120:377~384
Ballock RT / 1993 / TGF-beta1 prevents hypertrophy of epiphyseal chondrocytes: Regulation of gene expression for cartilage matrix proteins and metallo-proteases / Dev Biol 158:414~429
Bang OS / 2000 / Association of focal adhesion kinase with fibronectin and paxillin is required for precartilage condensation of chick mesenchymal cells / Biochem Biophys Res Commun 278:522~529
Amãlinei C / 2007 / Biology of metalloproteinases / Rom J Morphol Embryol 48:323~334
Aulthouse AL / 1987 / The detection of a precartilage, blastema-specific marker / Dev Biol 120:377~384
Ballock RT / 1993 / TGF-beta1 prevents hypertrophy of epiphyseal chondrocytes: Regulation of gene expression for cartilage matrix proteins and metallo-proteases / Dev Biol 158:414~429
Bang OS / 2000 / Association of focal adhesion kinase with fibronectin and paxillin is required for precartilage condensation of chick mesenchymal cells / Biochem Biophys Res Commun 278:522~529
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Regulation of Chondrogenesis by Protein Kinase C Signaling
한국동물학회 학술대회
1999 .01
-
Signallings of Integrin-FAK Interaction for Cell Condensation during the Chondrogenesis of Chick Wing Bud Mesenchymal Cell
한국동물학회 학술대회
1997 .01
-
$Ca^{2+}$ -ATPase Regulates the Intracellular $Ca^{2+}$ in in vitro Chondrogenesis of Limb Bud Mesenchymal Cells
한국동물학회 학술대회
1995 .01
-
Protein Kinase $C\alpha$ Is Involved in the Cell Condensation During Chondrogenesis in Vitro
Korean journal of biological sciences
2000 .01
-
Transforming growth factor-s differentially regulate chondrogenesis of mesenchymal cells from chick wing and leg bud
한국동물학회 학술대회
2001 .01
-
Activation of CREB by PKA Promotes the Chondrogeneic Differentiation of Chick Limb Bud Mesenchymal Cells
Animal cells and systems
2009 .01
-
Effect of PMA-Suppressed Membrane Ruffling in Chondrogenesis of Chick Fore Limb Bud Mesenchymal Cells
한국동물학회 학술대회
1999 .01
-
The pattern of protein phosphorylation by protein kinase C during chondrogenesis in vitro
한국동물학회 학술대회
1996 .01
-
MicroRNA-21 controls the development of osteoarthritis by targeting GDF-5 in chondrocytes
Experimental and Molecular Medicine
2014 .01
-
Curcumin inhibits cellular condensation and alters microfilament organization during chondrogenic differentiation of limb bud mesenchymal cells
Experimental and Molecular Medicine
2009 .01
-
Lysophosphatidylcholine Enhances Chondrogenesis by the Modulation of Protein Kinase C Isoform Expression
Korean journal of biological sciences
1998 .01
-
Inhibition of Chondrogenesis by Cytochalasin D in High Density Micromass Culture of Chick Mesenchymal Cells: Its Effects on Expression of $\alpha$-Smooth Muscle Actin and P-cadherin
Korean journal of biological sciences
2001 .01
-
Correction: Curcumin inhibits cellular condensation and alters microfilament organization during chondrogenic differentiation of limb bud mesenchymal cells
Experimental and Molecular Medicine
2020 .01
-
Fibroblasts in three dimensional matrices: cell migration and matrix remodeling
Experimental and Molecular Medicine
2009 .01
-
Correction: TiO2 nanotube stimulate chondrogenic differentiation of limb mesenchymal cells by modulating focal activity
Experimental and Molecular Medicine
2020 .01
-
Up-regulation of matrix metalloproteinase-9 in smooth muscle cell undergoing death
한국생명과학회 심포지움
2006 .09
-
$Ca^{2+}$ Enhanced the Cell-Cell Interactions via FN and Its Receptors at the Early Condensation Period of Chondrogenic Differentiation by Activating CREB through CaM II Kinase
한국동물학회 학술대회
1995 .01
-
Staurosporine and cytochalasin D induce chondrogenesis by regulation of actin dynamics in different way
Experimental and Molecular Medicine
2012 .01
-
Chondrogenic Differentiation of Human Mesenchymal Stem Cells on a Patterned Polymer Surface
대한임상검사과학회지
2015 .01
-
Ectopic expression of cyclooxygenase-2-induced dedifferentiation in articular chondrocytes
Experimental and Molecular Medicine
2008 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0