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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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To develop a new anti-dementia acetylcholinesterase (AChE) inhibitor from edible mushrooms, AChE inhibitory activities were determined on water and ethanol extracts of various edible mushrooms from oriental medicine markets and agriculture markets. As a result, the 70% ethanol extract from Pholiota adiposa fruiting body had the highest AChE inhibitory activity of 30.6, and its water extract also had an AChE inhibitory activity of 23.8%. Therefore, we finally selected P. adiposa as a potent anti-dementia AChE inhibitor-containing mushroom. The AChE inhibitor of P. adiposa was maximally extracted when its fruiting body was treated with water for 3hr at $70^{\circ}C$ and 70% ethanol for 12 hr at $70^{\circ}C$, respectively.
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참고문헌 (15)
참고문헌 신청
Dugu M / 2003 / Review of dementia / Mount Sinai J Med 70:45~53
이은나 / 2010 / Screening of a Potent Antidementia Acetylcholinesterase Inhibitor-containing Fruits and Optimal Extraction Conditions / 한국식품영양학회지 23(3):318~323
Ji-Su Lee / 2009 / Nutritional and Physicochemical Characteristics of the Antidementia Acetylcholinesterase- Inhibiting Methanol Extracts from Umbilicaria esculenta / Mycobiology 37(3):203~206
곽지현 / 2009 / 저장 조건에 따른 녹차 추출물의 acetylcholinesterase(AChE) 저해 효과 / 한국식품과학회지 41(4):435~440
장춘희 / 2003 / 광대싸리잎의 Acetylcholinesterase 활성 저해성분 / 생약학회지 34(1):14~17
이은나 / 2010 / Screening of a Potent Antidementia Acetylcholinesterase Inhibitor-containing Fruits and Optimal Extraction Conditions / 한국식품영양학회지 23(3):318~323
Ji-Su Lee / 2009 / Nutritional and Physicochemical Characteristics of the Antidementia Acetylcholinesterase- Inhibiting Methanol Extracts from Umbilicaria esculenta / Mycobiology 37(3):203~206
곽지현 / 2009 / 저장 조건에 따른 녹차 추출물의 acetylcholinesterase(AChE) 저해 효과 / 한국식품과학회지 41(4):435~440
장춘희 / 2003 / 광대싸리잎의 Acetylcholinesterase 활성 저해성분 / 생약학회지 34(1):14~17
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